A comparison of the clinical anesthetic efficacy of 4% articaine and 0.5% bupivacaine (both with 1:200,000 epinephrine) for lower third molar removal

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
Leonardo V L GregorioCarlos F Santos

Abstract

This study compared the clinical efficacy of 4% articaine (A200) and 0.5% bupivacaine (B200), both with 1:200,000 epinephrine, for lower third molar removal. Fifty patients underwent removal of symmetrically positioned lower third molars, in 2 separate appointments, under local anesthesia either with A200 or B200, in a double-blind, randomized, and crossover manner. Time to onset, duration of postoperative analgesia, duration of anesthetic action on soft tissues, intraoperative bleeding, and hemodynamic parameters were evaluated. A statistically significant difference between the time to onset of A200 (1.66 +/- 0.13 minutes) and B200 (2.51 +/- 0.21 minutes) was found (P < .05). There was no statistically significant difference in the duration of analgesia, whether the patient was subjected to osteotomy or not, regardless of the local anesthetic used (3 to 4 hours; P > .05). However, when patients received B200 they experienced a statistically significant longer period of anesthesia on the soft tissues as compared with when they had received A200 (around 5 hours and 4 hours, respectively, P < .05). The surgeon's rating of intraoperative bleeding was considered very close to minimal for both anesthetics. In the surgeries with ost...Continue Reading

Associated Clinical Trials

References

Dec 1, 1984·International Journal of Oral Surgery·R A Seymour, J G Walton
Feb 1, 1983·Oral Surgery, Oral Medicine, and Oral Pathology·P A Moore, J L Dunsky
Oct 1, 1984·Oral Surgery, Oral Medicine, and Oral Pathology·P A Moore
May 5, 1998·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·M NaguibM Attia
Mar 16, 2002·Current Topics in Medicinal Chemistry·Y A RuetschA Borgeat
Jun 22, 2005·Best Practice & Research. Clinical Anaesthesiology·Tom B Vree, Mathieu J M Gielen
Apr 7, 2006·Anesthesia Progress·Maria Cristina VolpatoFrancisco Carlos Groppo
Aug 1, 2006·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Bella L ColombiniCarlos F Santos
Oct 21, 2006·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Aleksa B Marković, Ljubomir Todorović
Aug 1, 2007·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·V BenetelloC F Santos
Nov 21, 2007·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Carlos F SantosJosé R P Lauris

❮ Previous
Next ❯

Citations

Jul 14, 2014·Acta Anaesthesiologica Taiwanica : Official Journal of the Taiwan Society of Anesthesiologists·Ashwin ThakareRahul Kathariya
Sep 18, 2013·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Khalid E El-Kholey
Dec 17, 2009·International Journal of Oral and Maxillofacial Surgery·B M B BrkovicD Stojic
Dec 2, 2014·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Claudia Resende LealRoberta Martinelli Carvalho
Dec 15, 2010·International Journal of Oral and Maxillofacial Surgery·P A K TrindadeC F Santos
Jun 27, 2012·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Paulo A K TrindadeCarlos F Santos
Apr 10, 2013·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Adriana M CalvoCarlos F Santos
Feb 5, 2014·Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical Society·Ahmed Al-Kahtani
Jul 24, 2015·Journal of Dental Research·A M SenesC F Santos
Apr 9, 2011·British Dental Journal·K E YappP Parashos
Jun 14, 2018·Brazilian Dental Journal·Luis Fernando SimonetiCarlos Ferreira Santos
Jul 11, 2018·The Cochrane Database of Systematic Reviews·Geoffrey St GeorgeAviva Petrie
Aug 29, 2020·Journal of the Korean Association of Oral and Maxillofacial Surgeons·Som SochendaNatthamet Wongsirichat
Jun 1, 2016·Journal of Dental Anesthesia and Pain Medicine·Yutthasak KriangcherdsakNatthamet Wongsirichat
Jun 1, 2016·Journal of Dental Anesthesia and Pain Medicine·Parmanand Dhanrajani, Patrick Chung
Jan 8, 2020·Annals of Maxillofacial Surgery·D Prasanna KumarNithin Varalakonda Manjunath
Feb 18, 2020·Clinical Oral Investigations·Ozlem VeliogluEmre Velioglu
Jan 17, 2014·Journal of Maxillofacial and Oral Surgery·Deepashri H KambalimathS M Agrawal
Sep 26, 2020·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Emerson Filipe de Carvalho NogueiraRicardo José de Holanda Vasconcellos
Feb 16, 2021·Journal of Dental Anesthesia and Pain Medicine·Alejandro Gago-GarcíaJesús Seco-Calvo
Nov 19, 2020·European Journal of Clinical Pharmacology·Giovana M WeckwerthCarlos F Santos
Jun 1, 2020·International Journal of Oral and Maxillofacial Surgery·O Camps-FontE Valmaseda-Castellón
Nov 25, 2020·The Journal of the American Dental Association·Laura Santos-SanzCosme Gay-Escoda
Jul 2, 2021·Heliyon·D Arboleda-ToroN M V Florez-Zapata

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Carlos F SantosJosé R P Lauris
The Journal of Craniofacial Surgery
Hécio Henrique Araújo de MoraisRicardo José de Holanda Vasconcellos
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
Bella L ColombiniCarlos F Santos
© 2022 Meta ULC. All rights reserved