PMID: 7396579Jul 1, 1980Paper

A comparison of the effects of membrane and bubble oxygenators on platelet counts and platelet size in elective cardiac operations

The Annals of Thoracic Surgery
H R TrumbullD M Nicoloff


To compare the effects of membrane and bubble oxygenators on platelet counts and the size of circulating platelets, serial hematocrits, platelet counts, and platelet sizing were measured in 23 patients undergoing elective cardiac operations. In 10 patients a bubble oxygenator was used and in 13, a SciMed membrane oxygenator. The two groups were statistically similar with respect to age, weight, time on bypass, and mean blood flow rates during bypass. It was found that platelet counts, when corrected for hemodilution, did not fall from control levels during or up to 24 hours after cardiopulmonary bypass in either group. In both groups, the relative number of platelets per gram of hemoglobin increased slightly during and after bypass, and this increase was significant in the bubble oxygenator group. The average size of circulating platelets increased only in the bubble oxygenator group, and then only in the one-day postoperative sample. These findings suggest that the membrane oxygenator offers no advantage with respect to preservation of platelets during cardiopulmonary bypass lasting up to 2 to 3 hours.


Jan 1, 1976·The Annals of Thoracic Surgery·V A Subramanian, R L Berger
Apr 1, 1978·The Annals of Thoracic Surgery·W R FriedenbergR D Sautter
Apr 1, 1978·The Annals of Thoracic Surgery·L H EdmundsT J Wilson
Mar 1, 1972·Transfusion·O M PikeR T Breckenridge
Jan 7, 1971·The New England Journal of Medicine·S K GargS Karpatkin
Apr 1, 1967·Circulation·E F BernsteinR L Varco
Dec 14, 1961·The New England Journal of Medicine·P J SCHMIDTA BARANOVSKY
Jul 1, 1963·Transfusion·E W SALZMAN


Jan 1, 1987·The American Journal of Emergency Medicine·J T AmsterdamR Zumwalt
Jan 9, 1999·Perfusion·J A HydeT R Graham
Nov 1, 1982·Anaesthesia and Intensive Care·V S Iyer, W J Russell

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