A comparison of the efficacy of 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:80,000 epinephrine in achieving pulpal anesthesia in maxillary teeth with irreversible pulpitis

Journal of Endodontics
Mohammad Dib KanaaJohn Gerard Meechan

Abstract

To assess the efficacy of buccal infiltrations of 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:80,000 epinephrine in achieving anesthesia in maxillary teeth with irreversible pulpitis. This randomized double-blind clinical trial included 100 patients diagnosed with irreversible pulpitis in maxillary teeth. Patients received 2.0 mL 4% articaine with 1:100,000 epinephrine or 2% lidocaine with 1:80,000 epinephrine in the buccal sulcus adjacent to the tooth with pulpitis. Before and every 2 minutes up to a maximum of 10 minutes after injection, the response of the test tooth was assessed using an electronic pulp tester. Successful pulp anesthesia was considered to have occurred when no response was obtained to the maximum stimulation (80 reading) of the pulp tester during the test period, at which time treatment commenced. Treatment was regarded as being successfully completed when it was associated with no pain. The time to onset of successful pulp anesthesia was recorded for each test tooth. Injection discomfort was recorded on standard 100-mm visual analog scales (VASs). Data were analyzed by the Chi-square and Student t tests. Fifty patients received articaine and 50 received lidocaine. Seventy-three of the 1...Continue Reading

References

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Citations

Jul 24, 2015·Journal of Dental Research·A M SenesC F Santos
Nov 1, 2013·Brazilian Dental Journal·Isabel Peixoto TortamanoRodney Garcia Rocha
Jul 11, 2018·The Cochrane Database of Systematic Reviews·Geoffrey St GeorgeAviva Petrie
Dec 15, 2018·BMC Medical Education·Christian KnipferFlorian Stelzle
Oct 18, 2013·Experimental Biology and Medicine·Ana Celeste OliveiraMiguel Alaminos
Aug 4, 2016·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Мarko J Milosavljevic, Slobodan M Jankovic
Dec 4, 2015·Dental Update·Tom Thayer
Apr 12, 2016·Australian Endodontic Journal : the Journal of the Australian Society of Endodontology Inc·Naichuan SuLiang Kou
Jan 15, 2019·Journal of Dental Anesthesia and Pain Medicine·Nelly Badr, Johan Aps
Jan 17, 2020·Journal of Dental Anesthesia and Pain Medicine·Gowri SivaramakrishnanKannan Sridharan
Jun 5, 2021·International Journal of Pharmaceutics·Qiman GaoFaleh Tamimi

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