PMID: 8995060Dec 1, 1996Paper

A comparison of the nucleotide sequences of the adk and recA genes of pathogenic and commensal Neisseria species: evidence for extensive interspecies recombination within adk

Journal of Molecular Evolution
E FeilB G Spratt

Abstract

The sequences of the adenylate kinase gene (adk) and the RecA gene (recA) were determined from the same isolates of Neisseria gonorrhoeae, N. meningitidis, N. lactamica, N. polysaccharea, N. cinerea, N. mucosa, N. pharyngis var. flava, N. flavescens, and N. animalis. The patterns of sequence divergence observed at adk and recA were very different. Dendrograms constructed from the recA data using two different algorithms were statistically robust and were congruent with each other and with the relationships between the species previously proposed using other data. In contrast, the dendrograms derived from the adk data were noncogruent with each other, and with those from the recA data, and were statistically poorly supported. These results, along with the uniform distribution of pairwise sequence divergences between the species at adk, suggest there has been a history of interspecies recombination within the adk gene of the human Neisseria species which has obscured the phylogenetic relationships between the species. This view was supported by Sawyer's runs test, and the Index of Association (IA) between codons, which provided significant evidence for interspecies recombination between the adk genes from the human Neisseria spec...Continue Reading

References

Nov 1, 1991·Journal of Bacteriology·D E Dykhuizen, L Green
Jan 3, 1991·Nature·J M SmithB G Spratt
Oct 1, 1988·Clinical Microbiology Reviews·J S Knapp
Dec 1, 1982·Journal of Bacteriology·J F GravesP F Sparling
Nov 7, 1995·Proceedings of the National Academy of Sciences of the United States of America·E FeilB G Spratt
Jun 1, 1994·Computer Applications in the Biosciences : CABIOS·P R ReevesR Lan
Oct 11, 1994·Proceedings of the National Academy of Sciences of the United States of America·K Nelson, R K Selander
Oct 1, 1994·Microbiology·S J Barrett, P H Sneath
Feb 15, 1994·Proceedings of the National Academy of Sciences of the United States of America·E F BoydR K Selander
Nov 1, 1993·Journal of General Microbiology·M O'Rourke, E Stevens
May 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·J M SmithB G Spratt
Feb 1, 1995·Evolution; International Journal of Organic Evolution·Frederick M Cohan

❮ Previous
Next ❯

Citations

Oct 6, 2004·Journal of Molecular Evolution·Yuuhiko TanabeMakoto M Watanabe
Jan 31, 2007·Proceedings of the National Academy of Sciences of the United States of America·W Ford Doolittle, Eric Bapteste
Mar 11, 2000·Molecular Biology and Evolution·S L Turner, J P Young
Jun 12, 1999·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·B G Spratt, M C Maiden
Nov 18, 2000·Infection and Immunity·O C StineJ A Johnson
Mar 24, 2005·Infection and Immunity·Julia S BennettMartin C J Maiden
Apr 20, 2005·Journal of Bacteriology·Yao-Hui SunChristoph Tang
Apr 28, 2001·Journal of Clinical Microbiology·D AlberU Vogel
Jun 16, 2006·Annual Review of Microbiology·Martin C J Maiden
Sep 1, 2005·PLoS Genetics·Eduardo P C RochaBénédicte Michel
Oct 15, 1998·Proceedings of the National Academy of Sciences of the United States of America·J S KrollP R Langford
Jan 3, 2001·Proceedings of the National Academy of Sciences of the United States of America·E J FeilB G Spratt
Sep 7, 2001·Annual Review of Microbiology·E J Feil, B G Spratt
Oct 18, 2016·Frontiers in Cellular and Infection Microbiology·Nídia CangiNathalie Vachiéry
Jul 12, 2002·Canadian Journal of Microbiology·Fajun ChenTom Hsiang
Sep 8, 1998·FEMS Microbiology Reviews·K M NielsenJ D van Elsas
Dec 16, 2000·Fungal Genetics and Biology : FG & B·J W TaylorM C Fisher
Oct 25, 2000·International Journal of Medical Microbiology : IJMM·M C Maiden

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.