PMID: 4292774Aug 1, 1967Paper

A comparison of the properties of fructose 1,6-diphosphatase, and the activities of other key enzymes of carbohydrate metabolism, in the livers of embryonic and adult rat, sheep and domestic fowl

The Biochemical Journal
J C Wallace, E A Newsholme

Abstract

1. The activities of some key enzymes of glycolysis and gluconeogenesis were measured in embryonic chick, sheep and rat livers. 2. In chicken the activities of hexokinase, phosphofructokinase and pyruvate kinase are low, but those of glucose 6-phosphatase and fructose diphosphatase are very high; the converse situation exists in the rat (Burch et al. 1963), but in sheep the activities of both phosphofructokinase and fructose diphosphatase are high, and the activities of hexokinase and glucose 6-phosphatase are low. These findings are discussed in relation to carbohydrate metabolism in these embryonic livers. 3. The regulatory properties of fructose diphosphatase from the embryonic livers of these three species were compared with the properties of the enzymes from adult animals. The inhibitions by AMP and fructose diphosphate and the effects of Mg(2+) and pH on the activities of adult and foetal fructose diphosphatase are almost identical. 4. It is concluded that regulatory properties are characteristic of fructose diphosphatase from embryonic and adult tissue, and the importance of this in relation to enzyme development is discussed.

Citations

Apr 1, 1970·The Journal of Pediatrics·A Sadeghi-NejadB Senior
Nov 1, 1976·Archives of Biochemistry and Biophysics·E E LengleS E Grossberg
Dec 1, 1971·The Proceedings of the Nutrition Society·J Pearce
Jun 5, 2014·Nutrition Research Reviews·Stéphane PanseratSergio Polakof
May 8, 2013·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Heidi E Harley
Sep 28, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Isabel Walter, Frank Seebacher
Oct 1, 1977·The American Journal of Physiology·D C Topping, W J Visek
Jun 22, 1970·Life Sciences. Pt. 2: Biochemistry, General and Molecular Biology·N K Sarkar
Jan 1, 1982·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·M Picardo, A J Dickson
Aug 15, 1972·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·V Lustig, J A Kellen
Jan 1, 1978·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·I E O'Neill, D R Langslow
Jan 1, 1983·The International Journal of Biochemistry·A J Dickson
Jan 1, 1984·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·A J Bate, A J Dickson
Jan 1, 1969·Archives of Biochemistry and Biophysics·K Sato, S Tsuiki

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.