A comparison of the susceptibility of the biting midge Culicoides imicola to infection with recent and historical isolates of African horse sickness virus

Medical and Veterinary Entomology
Gert J VenterJ T Paweska

Abstract

The susceptibility of Culicoides (Avaritia) imicola Kiefer (Diptera: Ceratopogonidae) to 21 isolates representing all nine known serotypes of African horse sickness virus (AHSV), recovered from clinical cases of the disease in South Africa during 1998-2004, was compared with its susceptibility to approximately 40-year-old isolates stored at the Agricultural Research Council-Onderstepoort Veterinary Institute. Field-collected C. imicola were fed through a chicken skin membrane on sheep blood spiked with one of the virus isolates to a concentration in the range of 5.6-7.5 log (10)TCID(50)/mL. After 10 days incubation at 23.5 degrees C, five of the nine historical serotypes (AHSV-1, -2, -3, -7 and -9) could not be isolated from C. imicola. All nine serotypes were recovered for the 21 recent isolates, for 16 of which the virus recovery rates were higher than for the corresponding historical isolates. These results emphasize the need to assess the oral susceptibility of local Culicoides populations to viruses in circulation during outbreaks in order to estimate their vector potential.

References

Jan 1, 1990·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·C HouseM L Berninger
Mar 2, 1999·Nature·M BaylisR Meiswinkel
Aug 6, 2003·Preventive Veterinary Medicine·R Meiswinkel, J T Paweska
Dec 24, 2003·Comparative Immunology, Microbiology and Infectious Diseases·Zhiyin ZhengYoshifusa Aizawa
Jul 9, 2004·Veterinary Research·Philip Scott Mellor, Christopher Hamblin
Nov 28, 2009·Medical and Veterinary Entomology·G J VenterJ T Paweska

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