For functional magnetic resonance imaging (fMRI), multi-voxel pattern analysis (MVPA) has been shown to be a sensitive method to detect areas that encode certain stimulus dimensions. By moving a searchlight through the volume of the brain, one can continuously map the information content about the experimental conditions of interest to the brain. Traditionally, the searchlight is defined as a volume sphere that does not take into account the anatomy of the cortical surface. Here we present a method that uses a cortical surface reconstruction to guide voxel selection for information mapping. This approach differs in two important aspects from a volume-based searchlight definition. First, it uses only voxels that are classified as grey matter based on an anatomical scan. Second, it uses a surface-based geodesic distance metric to define neighbourhoods of voxels, and does not select voxels across a sulcus. We study here the influence of these two factors onto classification accuracy and onto the spatial specificity of the resulting information map. In our example data set, participants pressed one of four fingers while undergoing fMRI. We used MVPA to identify regions in which local fMRI patterns can successfully discriminate whic...Continue Reading
Functional magnetic resonance imaging (fMRI) "brain reading": detecting and classifying distributed patterns of fMRI activity in human visual cortex
Patterns of fMRI activity dissociate overlapping functional brain areas that respond to biological motion
Testing key predictions of the associative account of mirror neurons in humans using multivariate pattern analysis
Primary motor cortex changes after amputation correlate with phantom limb pain and the ability to move the phantom limb
Decoding the individual finger movements from single-trial functional magnetic resonance imaging recordings of human brain activity
Combined effects of type 2 diabetes and hypertension associated with cortical thinning and impaired cerebrovascular reactivity relative to hypertension alone in older adults
Representations of Invariant Musical Categories Are Decodable by Pattern Analysis of Locally Distributed BOLD Responses in Superior Temporal and Intraparietal Sulci
Surface-Based fMRI-Driven Diffusion Tractography in the Presence of Significant Brain Pathology: A Study Linking Structure and Function in Cerebral Palsy
Representational models: A common framework for understanding encoding, pattern-component, and representational-similarity analysis
Neural Representations of Belief Concepts: A Representational Similarity Approach to Social Semantics
The Mirror Neurons Network in Aging, Mild Cognitive Impairment, and Alzheimer Disease: A functional MRI Study
Integrative and distinctive coding of visual and conceptual object features in the ventral visual stream
Ipsilateral finger representations in the sensorimotor cortex are driven by active movement processes, not passive sensory input
Spatially and Temporally Distinct Encoding of Muscle and Kinematic Information in Rostral and Caudal Primary Motor Cortex.
A method for anisotropic spatial smoothing of functional magnetic resonance images using distance transformation of a structural image
Chronic pain in children: structural and resting-state functional brain imaging within a developmental perspective.
CSF & Lymphatic System
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