A comparison of wall motion analysis and systolic left ventricular long axis function during dobutamine stress echocardiography

European Heart Journal
M B MishraJ B Chambers

Abstract

To compare long-axis function and wall motion analysis for the detection of significant coronary artery stenoses in patients with single and multivessel disease. We performed dobutamine stress echocardiography in 67 subjects, 14 with normal coronary anatomy, and 53 with significant coronary disease. A blunted increase in mean long-axis shortening of <0.25 cm was the best discriminator for coronary artery disease (sensitivity 85%, specificity 81%). Using this threshold, long axis function gave a sensitivity of 88% and specificity 89% for the detection of coronary artery disease in patients with normal resting wall motion while wall motion abnormality analysis had a sensitivity 73% and specificity 94%. Of 26 patients with a resting wall motion abnormality, 14 (54%) had multivessel disease. Long axis function detected multivessel disease in 12 of these (sensitivity 86%) compared with nine (sensitivity 64%) for wall motion analysis. Long axis function provides a promising, quantitative adjunct to wall motion analysis for the detection of coronary ischaemia using dobutamine stress echocardiography in patients with single and multivessel disease and with resting wall motion abnormalities.

Citations

Jul 15, 2009·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Konstantinos A TriantafyllouDimitrios Babalis
Feb 15, 2005·Ultrasound in Medicine & Biology·J KuoO T von Ramm
Sep 22, 2009·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Marcel L GeleijnseEric Boersma
Apr 26, 2007·Echocardiography·Marcel L GeleijnseFolkert J ten Cate

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