PMID: 2112346Jun 1, 1990Paper

A comparison of washed red blood cells versus packed red blood cells (AS-1) for cardiopulmonary bypass prime and their effects on blood glucose concentration in children

Anesthesiology
M P HoskingK R Williamson

Abstract

The effects on blood glucose concentrations of packed red blood cells (AS-1) (group I) versus washed red blood cells (group II) for cardiopulmonary bypass prime were compared in 20 infants weighing less than 10 kg undergoing cardiac surgical procedures. All patients were anesthetized with N2O/O2/isoflurane/fentanyl and received lactated Ringer's solution prior to bypass. Blood glucose concentrations prior to bypass were 85 +/- 15 mg/dl (mean +/- SD) in group I and 81 +/- 14 mg/dl in group II. Blood glucose concentrations were 210 +/- 21 mg/dl versus 78 +/- 14 mg/dl (P less than 0.001) 10 min after initiation of bypass, 241 +/- 48 mg/dl versus 107 +/- 28 mg/dl (P less than 0.001) prior to separation from bypass, and 214 +/- 52 mg/dl versus 97 +/- 19 mg/dl (P less than 0.001) after protamine administration in group I and group II, respectively. The use of washed red blood cells for cardiopulmonary bypass priming solution in infants significantly attenuates the increase in blood glucose concentration otherwise observed during cardiopulmonary bypass.

Citations

Jun 1, 1997·Journal of Cardiothoracic and Vascular Anesthesia·A AouifiJ J Lehot
May 7, 2016·Biochemical and Biophysical Research Communications·Maya AleshnickSaulius Butenas
Jan 21, 2016·The Cochrane Database of Systematic Reviews·Amy K KeirMichael J Stark
Feb 11, 2014·The Cochrane Database of Systematic Reviews·Kirstin L WilkinsonMichael F Murphy
Jul 8, 2020·Vox Sanguinis·Rebecca CardiganStephen Thomas
Jan 1, 1993·Perfusion·A G HillM Kurusz

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