PMID: 15228202Jul 2, 2004Paper

A comparison of yield in a non-systematic and a systematic review

Community Dental Health
M C DownerP M Speight

Abstract

To compare the results of a non-systematic (A) and a systematic review (B) of test performance in oral cancer and precancer screening in terms of literature coverage, and qualitative and quantitative information yield. For A, two databases were searched using basic search terms. Review B followed published guidelines. Nine databases were searched using three complex facets. In both reviews, one reviewer made the initial selection of relevant studies and, in A, carried out full text screening. In B, two independent reviewers carried out full text screening and then conferred on a final list of studies for inclusion and meta-analysis. In search A, 60 papers, and in B, 481 papers, were retrieved. Thirty from A, and 47 from B were selected for full text screening. From A, six papers, and from B, eight papers (six selected by the first reviewer and eight by the second; kappa = 0.83), were designated for inclusion in meta-analysis. The six papers from A were common to all selections. Seven papers were finally included in B. Compared with the non-systematic review, meta-analysis in the systematic review reduced the 95% CI for sensitivity from 0.594, 0.912 (= 0.318) to 0.713, 0.919 (= 0.189) resulting from the inclusion of a larger num...Continue Reading

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