A comparison: the efficacy of sevoflurane-nitrous oxide or propofol-nitrous oxide for the induction and maintenance of general anesthesia

Journal of Clinical Anesthesia
C A LienR E Kelly

Abstract

To compare sevoflurane-nitrous oxide with propofol-nitrous oxide for the induction and maintenance of anesthesia, and to determine the rates of recovery following each anesthetic. Randomized, controlled study. Teaching hospital. 50 ASA physical status I and II patients, ranging in age from 18 to 70 years. General anesthesia was induced with either sevoflurane or propofol and maintained with 60% to 70% nitrous oxide and either sevoflurane or a propofol infusion and supplemental fentanyl. At the conclusion of surgery, the oxygen flow was increased to 6 L/min and all anesthetics were discontinued simultaneously. Patients were monitored for the nature and speed of induction and emergency from anesthesia. Induction of anesthesia was significantly slower in the sevoflurane group than in the propofol group (2.0 +/- 1.1 vs. 0.8 +/- 0.5 min, respectively). The ease of induction and the time required for emergence from anesthesia were the same in both study groups (eye opening: 9.0 +/- 4.4 min vs. 8.0 +/- 5.0 min; following commands: 11.2 +/- 5.0 min vs. 9.8 +/- 6.9 min; extubation: 9.1 +/- 4.5 min vs. 8.6 vs. 5.1 min in the sevoflurane and propofol groups, respectively). Patients in the sevoflurane group experienced nausea and vomiting ...Continue Reading

References

Sep 1, 1992·Anesthesia and Analgesia·L R Ferrari, J V Donlon
Apr 1, 1992·Anesthesia and Analgesia·A BorgeatK Rifat
Feb 11, 1992·Anesthesia and Analgesia·E J FrinkB R Brown
Jan 1, 1992·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·R H Taylor, J Lerman
Feb 1, 1988·British Journal of Anaesthesia·T KirkpatrickW S Nimmo
Mar 1, 1988·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·M S SchellerB L Partridge
Oct 1, 1986·British Journal of Anaesthesia·N H KayE J Douglas
Dec 1, 1987·Anesthesia and Analgesia·E GeptsE J Douglas
Jul 1, 1987·Anesthesia and Analgesia·D P Strum, E I Eger
Oct 1, 1987·Anesthesia and Analgesia·E I Eger
Mar 1, 1987·Anesthesiology·T Katoh, K Ikeda
Aug 1, 1985·British Journal of Anaesthesia·G RollyH Mungroop
Mar 1, 1981·British Journal of Anaesthesia·E MajorW Aveling
Oct 1, 1995·Anesthesia and Analgesia·B FredmanP F White
Jan 1, 1995·Anesthesiology·F Dexter, J H Tinker

❮ Previous
Next ❯

Citations

May 8, 1999·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·S EinarssonJ P Bengtson
May 20, 2000·Journal of Clinical Anesthesia·J F HendrickxA M De Wolf
Apr 12, 2000·European Journal of Anaesthesiology·V A PedutoC Giorgini
Sep 9, 2006·Current Opinion in Anaesthesiology·Kristin Engelhard, Christian Werner
Apr 28, 2004·European Journal of Anaesthesiology·R Martín-LarrauriC Casimiro
Jun 27, 2000·Anesthesia and Analgesia·H S Joo, W J Perks
Mar 17, 2012·Journal of Neurophysiology·Yuchun ZhangJohn E Lisman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.