A comprehensive assessment of urinary iodine concentration and thyroid hormones in New Zealand schoolchildren: a cross-sectional study.

Nutrition Journal
S A SkeaffWinsome R Parnell

Abstract

Insufficient iodine in children's diets is of concern because thyroid hormones are needed for normal growth and development, particularly of the brain. This study aimed to carry out a comprehensive assessment of the iodine status of New Zealand schoolchildren using a range of biochemical indices suitable for populations (i.e. urinary iodine concentration) and individuals (i.e. thyroid hormones). The New Zealand National Children's Nutrition Survey was a cross-‒sectional survey of a representative sample of schoolchildren aged 5-‒14 years. Children were asked to provide a casual urine sample for the determination of urinary iodine concentration (UIC) and a blood sample for the determination of thyroglobulin (Tg), Thyroid Stimulating Hormone (TSH), free thyroxine (fT4) and free triiodothyronine (fT3). The median UIC was 68 μg/L (n = 1153), which falls between 50-‒99 μg/L indicative of mild iodine deficiency. Furthermore, 29% of children had an UIC <50 μg/L and 82% had an UIC <100 μg/L. The median Tg concentration was 12.9 μg/L, which also falls between 10.0-‒19.9 μg/L indicative of mild iodine deficiency. The Tg concentration of children with an UIC <100 μg/L was 13.9 μg/L, higher than the 10.3 μg/L in children with an UIC >100 μ...Continue Reading

References

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Citations

Aug 2, 2012·The British Journal of Nutrition·Sheila A Skeaff, Emily Lonsdale-Cooper
Apr 26, 2014·Thyroid : Official Journal of the American Thyroid Association·Zheng Feei Ma, Sheila A Skeaff
Mar 22, 2016·Clinical Endocrinology·P N Taylor, B Vaidya
Jul 28, 2016·Nutrients·Jody C MillerLisa A Houghton
Nov 3, 2017·Thyroid : Official Journal of the American Thyroid Association·Chi ChenYingli Lu
Jul 18, 2017·Journal of Environmental and Public Health·Declan T WaughWilliam Potter
Oct 24, 2020·Physiological Research·R BílekJ Jiskra

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Methods Mentioned

BETA
sandwich immunoassay

Software Mentioned

SAS
STATA

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