A comprehensive model for quantum noise characterization in digital mammography

Physics in Medicine and Biology
P MonninN W Marshall

Abstract

A version of cascaded systems analysis was developed specifically with the aim of studying quantum noise propagation in x-ray detectors. Signal and quantum noise propagation was then modelled in four types of x-ray detectors used for digital mammography: four flat panel systems, one computed radiography and one slot-scan silicon wafer based photon counting device. As required inputs to the model, the two dimensional (2D) modulation transfer function (MTF), noise power spectra (NPS) and detective quantum efficiency (DQE) were measured for six mammography systems that utilized these different detectors. A new method to reconstruct anisotropic 2D presampling MTF matrices from 1D radial MTFs measured along different angular directions across the detector is described; an image of a sharp, circular disc was used for this purpose. The effective pixel fill factor for the FP systems was determined from the axial 1D presampling MTFs measured with a square sharp edge along the two orthogonal directions of the pixel lattice. Expectation MTFs were then calculated by averaging the radial MTFs over all possible phases and the 2D EMTF formed with the same reconstruction technique used for the 2D presampling MTF. The quantum NPS was then estab...Continue Reading

References

Sep 1, 1989·Medical Physics·R M NishikawaR B Holmes
May 1, 1987·Journal of the Optical Society of America. A, Optics and Image Science·M RabbaniR Van Metter
Sep 1, 1987·Medical Physics·W HillenT Zaengel
Apr 1, 1995·Medical Physics·W Que, J A Rowlands
Nov 26, 1998·Medical Physics·W G JiJ A Rowlands
Jun 10, 2000·Journal of Digital Imaging·P LeblansP Willems
Dec 28, 2002·Physics in Medicine and Biology·J A Rowlands
Oct 19, 2004·Medical Physics·Wei ZhaoJ A Rowlands
Dec 14, 2004·Medical Physics·Aldo BadanoKyle J Myers
Dec 14, 2004·Medical Physics·Brandon D GallasKyle J Myers
Mar 5, 2010·IEEE Transactions on Medical Imaging·Srinivasan Vedantham, Andrew Karellas
Feb 10, 2011·Medical Physics·Jesse TanguayIan A Cunningham
Jun 28, 2011·Physics in Medicine and Biology·N W MarshallF R Verdun
Feb 11, 2012·Medical Physics·Nicholas W MarshallHilde Bosmans
Oct 6, 2014·Medical Physics·J XuJ H Siewerdsen
Jan 8, 2015·Medical Physics·Jesse TanguayIan A Cunningham

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