A Comprehensive Program for the Enhancement of Accrual to Clinical Trials

Annals of Surgical Oncology
Mark PorterWilliam E Carson

Abstract

The Ohio State University Comprehensive Cancer Center (OSUCCC) embarked on a single institution campaign over 2 years to enhance the enrollment of cancer patients into therapeutic clinical trials. The goal of this campaign was to achieve a 40 % increase in accrual over a 2-year period. The entire process of accruing patients to clinical trials at the OSUCCC was carefully evaluated and broken down into several interlocking components. The four key areas of emphasis were as follows: (i) tasking of OSUCCC leadership with increased oversight of the entire process; (ii) education of all stakeholders [patients, their families, nurses and staff, physicians (both internal and external), Disease-Specific Committees (DSCs), and the OSUCCC leadership] as to the purpose, advantages, and availability of clinical trials, with an emphasis on accrual to cancer clinical trials (CCTs) being a critical function of all OSUCCC employees; (iii) increased oversight of the portfolio of clinical trials by DSCs; and (iv) optimization of accrual operations and infrastructure center-wide. The accrual goal was achieved a full 4 months ahead of schedule. In total, 2327 patients were accrued to therapeutic clinical trials over the course of this 2-year campa...Continue Reading

References

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Nov 26, 2015·Nature Reviews. Clinical Oncology·Charles M BalchJohn E Niederhuber

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Citations

Jun 9, 2019·Neuro-oncology·Eudocia Q LeePatrick Y Wen
Dec 2, 2020·Urologic Oncology·Kristian D StenslandAlireza Moinzadeh
Apr 27, 2018·Contemporary Clinical Trials Communications·Jeffrey J Hardesty, Norma F Kanarek
Jun 26, 2021·Contemporary Clinical Trials Communications·Seunghee MargeviciusNeal J Meropol

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