A Comprehensive Review of Analgesia and Pain Modalities in Hip Fracture Pathogenesis

Current Pain and Headache Reports
Anis DizdarevicKarina Gritsenko

Abstract

Hip fracture is common in the elderly population, painful and costly. The present investigation was undertaken to review epidemiology, socio-economic and medical implications, relevant anatomy, and anesthetic and pain modalities of hip fracture. A literature search of PubMed, Ovid Medline, and Cochrane databases was conducted in December 2018 to identify relevant published clinical trials, review articles, and meta-analyses studies related to anesthetic and pain modalities of hip fracture. The acute pain management in these situations is often challenging. Common issues associated with morbidity and mortality include patients' physiological decrease in function, medical comorbidities, and cognitive impairment, which all can confound and complicate pain assessment and treatment. Perioperative multidisciplinary and multimodal approaches require medical, surgical, and anesthesiology teams employing adequate preoperative optimization. Reduction in pain and disability utilizing opioid and non-opioid therapies, regional anesthesia, patient-tailored anesthetic approach, and delirium prevention strategies seems to ensure best outcomes.

References

Jun 6, 1996·The New England Journal of Medicine·J D Zuckerman
Sep 15, 1998·Journal of the American Geriatrics Society·K S FeldtS Miles
May 9, 2000·Journal of Pain and Symptom Management·R S Morrison, A L Siu
May 24, 2000·British Journal of Anaesthesia·S C UrwinR Griffiths
Jun 16, 2000·Journal of the American Geriatrics Society·E R MarcantonioN M Resnick
Feb 28, 2002·Archives of Internal Medicine·Jane McCuskerEric Belzile
Feb 1, 2003·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·R Sean MorrisonAlbert L Siu
Jun 7, 2003·Pain·Sean R MorrisonAlbert L Siu
Nov 18, 2003·British Journal of Haematology·Marieke Torn, Frits R Rosendaal
Sep 8, 2006·British Journal of Anaesthesia·P AlbaladejoUNKNOWN French Society of Anesthesiology and Intensive Care
Nov 23, 2006·Journal of the American College of Surgeons·Florence E TurrentineR Scott Jones
Mar 4, 2008·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Toshiya ShigaYoko Ohe
Aug 9, 2008·Clinical Interventions in Aging·Diane L ChauLwin M Cho
Aug 20, 2009·Journal of Orthopaedics and Traumatology : Official Journal of the Italian Society of Orthopaedics and Traumatology·George MouzopoulosMichalis Kaminaris
Oct 15, 2009·Anesthesiology Clinics·Sheila Ryan Barnett
Nov 26, 2010·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·T J LugerJ Kreutziger
Nov 12, 2010·Age and Ageing·Andrew Clegg, John B Young
Aug 17, 2011·Annals of Internal Medicine·Ahmed M Abou-SettaC Allyson Jones
Sep 20, 2011·Best Practice & Research. Clinical Anaesthesiology·Julia C ColdreyPamela E Macintyre
May 2, 2012·The American Journal of Nursing·Ember E BensonBill Ong
Aug 30, 2012·Medical Gas Research·Nicole R Van AllenJohn H Zhang
Jan 22, 2013·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Saifee RashiqDonna M Dryden
Apr 25, 2013·Anesthesiology·Stavros G MemtsoudisNigel E Sharrock
Jun 14, 2013·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Francesca L BeaudoinOtto Liebmann
Jul 3, 2013·Korean journal of anesthesiology·Seung Dong KimDae Lim Jee
Oct 8, 2014·Anesthesiology and Pain Medicine·Hamid Reza AmiriSaeid Safari
Oct 10, 2014·Anesthesiology·Jacques BoddaertBruno Riou
Nov 6, 2014·Journal of the American Geriatrics Society·Dallas P SeitzPaula A Rochon
Jan 28, 2015·The Journal of the American Academy of Orthopaedic Surgeons·Karl C RobertsKaitlyn Sevarino
Jan 28, 2015·The Journal of the American Academy of Orthopaedic Surgeons·Karl C Roberts, W Timothy Brox
Feb 6, 2015·The Journal of Bone and Joint Surgery. American Volume·Mohammad A HelwaniHeiko A Kaiser

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Citations

Nov 26, 2020·The Cochrane Database of Systematic Reviews·Joanne Guay, Sandra Kopp
Apr 10, 2021·Clinical Orthopaedics and Related Research·Marianne Comeau-Gauthier, Mohit Bhandari
Jul 30, 2021·Current Opinion in Anaesthesiology·Levin GaripSam Van Boxstael

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