A Comprehensive Review of Treatment Options for Premenstrual Syndrome and Premenstrual Dysphoric Disorder

Journal of Psychiatric Practice
Shalini Maharaj, Kenneth Trevino

Abstract

Premenstrual dysphoric disorder (PMDD) is a severe form of premenstrual syndrome that involves a combination of emotional and physical symptoms that result in significant functional impairment. Because of the debilitating nature of PMDD, multiple treatment options have been considered. This review provides a comprehensive overview of these therapeutic regimens to help health care professionals provide adequate treatment for PMDD and premenstrual syndrome. The treatments that are reviewed are organized into the following categories: psychiatric, anovulatory, supplements, herbal, nonpharmacological, and other. Selective serotonin reuptake inhibitors have been established as the first-line treatment for PMDD. Although luteal phase or continuous dosing can be used, additional research is needed to more thoroughly compare the efficacies and differential symptom response of continuous, semi-intermittent, luteal phase, and symptoms-onset dosing. The psychiatric medications venlafaxine, duloxetine, alprazolam, and buspirone have also been found to be useful treatments for PMDD. Various anovulatory-related treatments have demonstrated efficacy; however, the use of some of these treatments remains limited due to potential side effects an...Continue Reading

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Apr 5, 2019·Journal of the American Medical Informatics Association : JAMIA·Jisan Lee, Jeongeun Kim
Sep 30, 2016·Pharmacological Reviews·Birgit M DietzJudy L Bolton
Mar 10, 2017·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Petra StuteMichael von Wolff
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Jan 19, 2021·Advanced Biomedical Research·Fatemeh RajabiMohammad Javad Tarrahi

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