Abstract
Tephrosia purpurea (L.) Pers. is a well-known plant in Ayurveda and named "Sarwa wranvishapaka" for its property to heal wounds. Traditionally, it is practiced for impotency, asthma, dyspepsia, hemorrhoids, syphilis gonorrhea, rheumatism, enlargement of kidney and spleen. It is an important component of herbal preparations like Tephroli and Yakrifti used to cure liver disorders. Various phytocompounds including pongamol, purpurin, purpurenone, tephrosin, bulnesol, tephrostachin, β-sitosterol, and so on have been reported. Modern pharmacological studies have shown that the plant have wound healing, antileishmanial, anticarcinogenic, antimicrobial, antioxidant, hepatoprotective, antifertility, antispermatogenic, anti-diarrheal, diuretic, and insecticidal properties. Acetylcholinesterase inhibitory action reported from this plant aids its utilization for the development of drugs for Alzheimer's and dementia neurological disorders. Among the known active compounds of T. purpurea, tephrostachin is responsible for antiplasmodial activity, tephrosin, pongaglabol, and semiglabrin exerts antiulcer activity while quercetin, rutin, β-sitosterol, and lupeol are mainly responsible for its anti-inflammatory and anti-cancer properties. From d...Continue Reading
References
Jan 1, 1975·Journal of Pharmaceutical Sciences·P H DoukasR S Thompson
Jul 1, 1990·Journal of Ethnopharmacology·S C ChhabraE N Mshiu
Feb 1, 1986·Journal of Ethnopharmacology·S A KhalidJ B Jensen
Jan 1, 1980·Virchows Archiv. A, Pathological Anatomy and Histology·H PopperR H Purcell
Oct 10, 1997·Journal of Natural Products·L C ChangA D Kinghorn
Feb 25, 1999·Journal of Ethnopharmacology·S K MitraS Gopumadhavan
May 26, 1999·Journal of Ethnopharmacology·P A De Smet
Nov 30, 1999·The British Journal of Oral & Maxillofacial Surgery·Y KubotaK Shirasuna
May 18, 2000·Organic Letters·L C ChangA D Kinghorn
Nov 4, 2000·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·L D WhighamR L Atkinson
Feb 24, 2001·Phytochemistry·A F MagalhãesS C Queiroz
Mar 13, 2001·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·M SaleemS Sultana
Mar 13, 2001·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·M SaleemS Sultana
May 22, 2002·Journal of Ethnopharmacology·A K SinghJ S Singh
Jul 12, 2002·Phytotherapy Research : PTR·Cecília T T BlattA Douglas Kinghorn
May 3, 2003·Fitoterapia·A S DamreM N Saraf
Aug 12, 2003·Journal of Medical Microbiology·T Dam, C R Babu
Jul 16, 2005·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·N AliT Yoshizawa
Jun 30, 2006·Journal of Ethnopharmacology·Santram LodhiA K Singhai
Jul 19, 2006·Clinical Microbiology Reviews·Johannes G KustersErnst J Kuipers
May 29, 2007·Journal of Ethnopharmacology·V Duraipandiyan, S Ignacimuthu
Dec 7, 2007·Journal of Ethnopharmacology·Ramar Perumal SamySavarimuthu Ignacimuthu
Jun 24, 2008·Journal of Ethnopharmacology·Akhilesh K TamrakarArvind K Srivastava
Nov 11, 2008·Journal of Chromatography. a·Bouthaina Ben AmorKarim Allaf
Dec 9, 2008·Journal of Ethnopharmacology·Amit KhatriShyam S Agrawal
May 12, 2009·Journal of Ethnopharmacology·Kumari Poonam, Gopal S Singh
May 27, 2009·Journal of Ethnopharmacology·Annalakshmi ChinniahPratap K Das
Jun 9, 2009·Journal of Ethnopharmacology·Esra Küpeli AkkolErdem Yeşilada
Jul 7, 2009·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·M J ChavanD B Shinde
Sep 8, 2009·Phytochemistry·Mohamed-Elamir F HegazyPaul W Paré
Mar 11, 2010·Journal of Ethnopharmacology·Bhuvaneshwar UpadhyayAshwani Kumar
May 22, 2010·Clinical Rheumatology·Mariela L PazJuliana Leoni
Jul 29, 2010·The Journal of Pharmacy and Pharmacology·Edakkadath R SindhuRamadasan Kuttan
Oct 12, 2010·Journal of Agricultural and Food Chemistry·Jun Ho KimYoung Jun Kim
Dec 15, 2010·Journal of Diabetes·Rajnish GuptaR S Gupta
Feb 5, 2011·Journal of Ethnopharmacology·Muniappan Ayyanar, Savarimuthu Ignacimuthu
Apr 23, 2011·Journal of Natural Products·Mohamed-Elamir F HegazyPaul W Paré
Jul 7, 2011·Molecular Autism·Donald C RojasSusan Hepburn
Jul 9, 2011·Lipids·William GilbertLatha Devareddy
Jul 21, 2011·Asian Pacific Journal of Tropical Medicine·D J Taur, R Y Patil
Aug 2, 2011·Asian Pacific Journal of Tropical Medicine·Vishal Gulecha, Thangavel Sivakuma
Mar 1, 2010·Pharmacognosy Research·Ali K KhalafalahAbou-El-Hamd H Mohamed
Oct 4, 2011·Journal of Pharmacy & Bioallied Sciences·Sabiha SumbulAkhtar Mohd
Oct 5, 2011·Asian Pacific Journal of Tropical Medicine·R SivakumarP Rajasekar
Mar 22, 2012·Journal of Dietary Supplements·D AshokkumarMalaya Gupta
Jul 11, 2012·The Journal of Pharmacy and Pharmacology·Talib HussainChandana Venkateswara Rao
Oct 4, 2012·Diabetes Care·Rebecca L ThomasDavid R Owens
Mar 1, 2007·Indian Journal of Clinical Biochemistry : IJCB·P PavanaS Manoharan
Apr 16, 2013·Experimental Parasitology·L E FerreiraR O Beleboni
Jul 11, 2013·Journal of Ethnopharmacology·Adeyemi O Aremu, Johannes Van Staden