A comprehensive review on synthetic approach for antimalarial agents

European Journal of Medicinal Chemistry
Ajay KumarDhirender Kaushik

Abstract

Malaria has emerged as a major health problem worldwide after the appearance of resistant strains of Plasmodium falciparum to the most of antimalarial drugs. The development of resistance by the parasite against first line as well as second line antimalarial drugs has drawn attention to develop new drugs to alleviate the disease burden. Therefore, there is a great need for new antimalarial drugs with improved attributes over older therapies. This review is primarily addressed to description of the recent advances in the synthesis of heterocyclic compound as antimalarial agents which can facilitate the development of more potent and effective antimalarial agents.

References

Nov 1, 1975·Journal of Medicinal Chemistry·P BlumbergsA Markovac
Jan 1, 1981·Medicinal Research Reviews·T R Sweeney
Feb 1, 1997·International Journal for Parasitology·M Foley, L Tilley
Mar 21, 1998·Pharmacology & Therapeutics·P M O'NeillB K Park
Aug 27, 1998·Pharmacology & Therapeutics·M Foley, L Tilley
Apr 13, 2000·Annual Review of Entomology·J Hemingway, H Ranson
Feb 24, 2001·Bioorganic & Medicinal Chemistry Letters·Gabriel Navarrete-VázquezR Castillo
Sep 20, 2001·Current Medicinal Chemistry·Prem M S Chauhan, S K Srivastava
Feb 8, 2002·Nature·Brian Greenwood, Theonest Mutabingwa
Feb 8, 2002·Nature·Jeffrey Sachs, Pia Malaney
May 30, 2002·Journal of the American Chemical Society·Adam F LittkeGregory C Fu
Aug 6, 2002·European Journal of Medicinal Chemistry·Pascal RathelotPatrice Vanelle
Dec 7, 2002·Bioorganic & Medicinal Chemistry·Thomas R WebbKenneth A Jacobson
Mar 7, 2003·Journal of Medicinal Chemistry·Gary H PosnerTheresa A Shapiro
Mar 20, 2003·Trends in Parasitology·J Kevin Baird, Karl H Rieckmann
Mar 28, 2003·European Journal of Medicinal Chemistry·Mariola AndrzejewskaZygmunt Kazimierczuk
Apr 8, 2003·Current Medicinal Chemistry·Arun KumarPrem M S Chauhan
Aug 21, 2003·Bioorganic & Medicinal Chemistry·Mariola AndrzejewskaZygmunt Kazimierczuk
Aug 22, 2003·The Journal of Biological Chemistry·Shailendra Kumar SharmaAvadhesha Surolia
Oct 7, 2003·Bioorganic & Medicinal Chemistry·Suryanarayana VangapanduRahul Jain
Oct 7, 2003·Bioorganic & Medicinal Chemistry·Gabriel Navarrete-VázquezRafael Castillo
Dec 23, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J Kevin BairdStephen L Hoffman
Apr 24, 2004·Trends in Parasitology·Mayfong MayxayNicholas J White
Aug 25, 2004·Trends in Parasitology·Peter A ZimmermanJames W Kazura
Oct 27, 2004·Bioorganic & Medicinal Chemistry Letters·Yohan Boursereau, Iain Coldham
Dec 8, 2004·Bioorganic & Medicinal Chemistry Letters·Advait A JoshiC L Viswanathan
Jan 25, 2005·Bioorganic & Medicinal Chemistry Letters·Axel G GriesbeckReto Brun
Feb 3, 2005·Bioorganic & Medicinal Chemistry Letters·Peter B MadridR Kiplin Guy
May 10, 2005·Bioorganic & Medicinal Chemistry Letters·Anu AgarwalPrem M S Chauhan
May 10, 2005·Bioorganic & Medicinal Chemistry·Meenakshi JainRahul Jain
May 13, 2005·Journal of Medicinal Chemistry·José N DomínguezPhilip J Rosenthal
Jun 1, 2005·Bioorganic & Medicinal Chemistry Letters·Anu AgarwalPrem M S Chauhan
Aug 2, 2005·Bioorganic & Medicinal Chemistry·Anna SparatoreDonatella Taramelli
Aug 2, 2005·Bioorganic & Medicinal Chemistry·Anu AgarwalPrem M S Chauhan
Sep 20, 2005·Bioorganic & Medicinal Chemistry Letters·Sanjay Babu KatiyarPrem M S Chauhan

Citations

Aug 22, 2015·European Journal of Medicinal Chemistry·Sofia A SantosAlexandra Paulo
Jan 18, 2016·European Journal of Medicinal Chemistry·Nalmala DevenderRama Pati Tripathi
Aug 28, 2015·European Journal of Medicinal Chemistry·Mohammad ShaquiquzzamanMohammad Mumtaz Alam
Feb 6, 2017·Journal of Ethnopharmacology·Bertha ChithamboRui W M Krause
Feb 18, 2016·Angewandte Chemie·Tim WezemanStefan Bräse
Dec 28, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Alina SecrieruMaria Lurdes Santos Cristiano
Oct 31, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Seong-Min LeeDongyun Shin

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