A comprehensive strategy in donor acceptance: Impact on pediatric waitlist and heart transplant outcomes.

Pediatric Transplantation
Nathanya Baez HernandezRyan J Butts

Abstract

Significant inter- and intra-center practice variability is present in pediatric donor heart acceptability. This may contribute to variation in the donor refusal rate and may impact waitlist time, morbidity, mortality, and transplant rates. In order to reduce practice variability, our center developed and implemented a comprehensive strategy regarding donor acceptance in September 2017. The aim of this study was to assess the impact of this strategy on waitlist time and outcomes as well as early post-transplant outcomes. We performed a single-center, retrospective analysis of all pediatric (<18 years) patients listed for single-organ heart transplant at our center from September 2015 to September 2018. Patients were divided into those listed before (Group 1) and after implementation of the comprehensive strategy (Group 2). The primary end-point was waitlist time. Secondary end-points included waitlist removal due to death or clinical deterioration, donor refusals per listed patient, early post-transplant outcomes (graft failure, mechanical ventilation time, inotropic support, length of hospital stay) and 1-year post-transplant survival. Of 78 listed patients, 54 were transplanted (29 in Group 1), 9 were removed due to death or ...Continue Reading

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Citations

May 29, 2021·The Journal of Thoracic and Cardiovascular Surgery·Shriprassad DeshpandeBahaaldin Alsoufi
Aug 27, 2021·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Deborah Kozik, Bahaaldin Alsoufi
Oct 5, 2021·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Alison E Butler, Gretchen B Chapman
Jan 27, 2022·Pediatrics·Brian HicknerAbbas Rana

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