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A computational framework for detecting signatures of accelerated somatic evolution in cancer genomes

bioRxiv

Aug 16, 2017

Kyle S SmithSubhajyoti De

Abstract

By accumulation of somatic mutations, cancer genomes evolve, diverging away from the genome of the host. It remains unclear to what extent somatic evolutionary divergence is comparable across different regions of the cancer genome versus concentrated in specific genomic elements. We pre...read more

Mentioned in this Paper

Biochemical Pathway
Patterns
Genome
Somatic Mutation
Molecular Profiling
Genomics
Genomic DNA
Chromatin Location
Cancer Promoting Genes
Whole Genome Sequencing
15
6
Paper Details
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A computational framework for detecting signatures of accelerated somatic evolution in cancer genomes

bioRxiv

Aug 16, 2017

Kyle S SmithSubhajyoti De

PMID: 990177261

DOI: 10.1101/177261

Abstract

By accumulation of somatic mutations, cancer genomes evolve, diverging away from the genome of the host. It remains unclear to what extent somatic evolutionary divergence is comparable across different regions of the cancer genome versus concentrated in specific genomic elements. We pre...read more

Mentioned in this Paper

Biochemical Pathway
Patterns
Genome
Somatic Mutation
Molecular Profiling
Genomics
Genomic DNA
Chromatin Location
Cancer Promoting Genes
Whole Genome Sequencing
15
6

Similar Papers Found In These Feeds

BioRxiv Preprints

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

Comparative Sequencing

Inter/Intra-Species: Comparative Sequencing describes the sequencing techniques that compare between and within species genomes. Discover the latest research on comparative sequencing of inter/intra-species here.

Related Papers

Nucleic Acids Research

Signatures of accelerated somatic evolution in gene promoters in multiple cancer types

Nucleic Acids ResearchMay 3, 2015
Kyle S SmithSubhajyoti De
Paper Details
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