A computer-controlled, continuously circulating, hot irrigating system for endometrial ablation

American Journal of Obstetrics and Gynecology
M S BaggishS Griffey

Abstract

This study evaluated the efficacy of a computer-controlled thermal catheter system to ablate the endometrium by use of 5 to 15 ml of hot saline solution. Five in vivo sheep uteri and 32 freshly excised human uteri were studied by inserting a self-contained heater catheter equipped with thermocouples and circulating hot saline solution for 15 minutes within the uteri at various temperature settings ranging from 60 degrees C to 80 degrees C. The uteri were grossly examined and microscopically evaluated by hematoxylin and eosin and reduced nicotinamide adenine dinucleotide-diaphorase stains for degree of acute destruction, depth of thermal injury, and predicted viability. All 80 degrees C sheep treatments resulted in complete loss of viability at mucosal, submucosal, and myometrial levels. In human uteri temperatures > or = 80 degrees C produced grossly recognizable thermal damage to the endometrium. Full-thickness irreversible damage was seen in the endometrium. Loss of viability was also demonstrated 1 to 3 mm deep in the superficial myometrium. Intrauterine pressure was demonstrated to range from 20 to 40 mm Hg, with a mean of 26 mm Hg. No leakage of fluid from the oviducts was observed. The data presented here demonstrate that...Continue Reading

References

Aug 1, 1988·American Journal of Obstetrics and Gynecology·M S Baggish, P Baltoyannis

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Citations

Oct 18, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Y PerlitzM Ben-Ami
Jan 19, 1999·Obstetrical & Gynecological Survey·S A StabinskyJ L Breen
Jul 31, 1999·British Journal of Obstetrics and Gynaecology·D A HodgsonL Hirschowitz
Feb 24, 2001·BJOG : an International Journal of Obstetrics and Gynaecology·C Kremer, S Duffy
Jun 17, 2000·Obstetrics and Gynecology Clinics of North America·J M Cooper, M L Erickson
Jan 29, 2000·The Journal of the American Association of Gynecologic Laparoscopists·J D DobakD E Townsend
Dec 1, 1996·American Journal of Obstetrics and Gynecology·J B Unger, G R Meeks
Aug 31, 2013·The Cochrane Database of Systematic Reviews·Anne LethabyJane Marjoribanks
Jan 23, 2019·The Cochrane Database of Systematic Reviews·Magdalena Bofill RodriguezCindy Farquhar

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