A continuum mechanics-based musculo-mechanical model for esophageal transport

Journal of Computational Physics
Wenjun KouNeelesh A Patankar

Abstract

In this work, we extend our previous esophageal transport model using an immersed boundary (IB) method with discrete fiber-based structural model, to one using a continuum mechanics-based model that is approximated based on finite elements (IB-FE). To deal with the leakage of flow when the Lagrangian mesh becomes coarser than the fluid mesh, we employ adaptive interaction quadrature points to deal with Lagrangian-Eulerian interaction equations based on a previous work (Griffith and Luo [1]). In particular, we introduce a new anisotropic adaptive interaction quadrature rule. The new rule permits us to vary the interaction quadrature points not only at each time-step and element but also at different orientations per element. This helps to avoid the leakage issue without sacrificing the computational efficiency and accuracy in dealing with the interaction equations. For the material model, we extend our previous fiber-based model to a continuum-based model. We present formulations for general fiber-reinforced material models in the IB-FE framework. The new material model can handle non-linear elasticity and fiber-matrix interactions, and thus permits us to consider more realistic material behavior of biological tissues. To valida...Continue Reading

References

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Feb 15, 2006·Computer Methods in Applied Mechanics and Engineering·Wing Kam LiuHuayi Hsu
May 7, 2014·International Journal for Numerical Methods in Biomedical Engineering·Hao GaoBoyce E Griffith
Mar 1, 2012·International Journal for Numerical Methods in Biomedical Engineering·Boyce E Griffith
Jun 27, 2015·American Journal of Physiology. Gastrointestinal and Liver Physiology·Wenjun KouNeelesh A Patankar
Jul 21, 2015·Journal of Computational Physics·Wenjun KouNeelesh A Patankar
Apr 21, 2017·International Journal for Numerical Methods in Biomedical Engineering·Boyce E Griffith, Xiaoyu Luo

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Citations

Apr 21, 2017·International Journal for Numerical Methods in Biomedical Engineering·Boyce E Griffith, Xiaoyu Luo
Jan 6, 2017·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·W KouN A Patankar
Feb 15, 2021·Artificial Intelligence in Medicine·Wenjun KouMozziyar Etemadi
Mar 3, 2021·Biomechanics and Modeling in Mechanobiology·Sourav HalderNeelesh A Patankar
Jun 3, 2020·Computer Methods in Applied Mechanics and Engineering·Ben Vadala-RothBoyce E Griffith
Dec 6, 2019·Journal of Computational Physics·Ebrahim M KolahdouzBoyce E Griffith
Feb 25, 2021·Journal of Biomechanical Engineering·Shashank AcharyaNeelesh A Patankar
Apr 11, 2021·Proceedings of the National Academy of Sciences of the United States of America·Alexander P HooverLaura A Miller
May 11, 2021·Frontiers in Neuroscience·Leo K ChengNiranchan Paskaranandavadivel
Jul 19, 2021·Biomechanics and Modeling in Mechanobiology·Hallie ElichAaron L Fogelson

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