A controlled study of the time-course of breath alcohol concentration after moderate ingestion of ethanol following a social drinking session

Forensic Science International : Synergy
Jesús BarquínAntonio F Hernández

Abstract

This paper evaluates the breath alcohol concentration (BrAC), nausea (feeling of being slightly intoxicated) and subjective driving performance after ingesting a moderate dose of alcohol in the presence of a light meal, which intends to approach a social drinking setting. 119 healthy individuals (69 males and 50 females, aged 21.7+/-3.0) ingested three glasses of wine (95mL each) and their BrAC was determined by an Alcotest 7410 at 15, 30, 45, 60, 90 and 120min post-drinking. 46% of females and no male subjects exceeded a BrAC of 0.25mg/L, the legal limit for driving fixed by some Western countries. 53% of the study population felt nausea during the experimental session and 20% self-reported impairment of their driving skills. In both cases these subjective effects were more pronounced in females. The major determinants of mean BrAC were time post-drinking, gender (male) and body mass index (BMI), all these variables being inversely associated. Females and individuals with a BMI lower than 22.5kg/m(2) were at an increased risk of exceeding the legal limit of BrAC. The feeling of nausea was significantly associated with gender (females), the ingestion of up to 2 drinks on weekdays, and having exceeded a BrAC of 0.25mg/L during t...Continue Reading

References

Nov 1, 1987·Clinical Pharmacokinetics·N H Holford
Aug 1, 1997·Alcoholism, Clinical and Experimental Research·F C BreslinH Cappell
Sep 26, 2000·Alcoholism, Clinical and Experimental Research·M S MumenthalerJ A Yesavage
Apr 21, 2004·Epidemiology·Jennie ConnorRod Jackson
Jun 7, 2005·Forensic Science International : Synergy·Thomas W M TamVincent K K Mok

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Citations

Feb 6, 2013·Addictive Behaviors·Elizabeth R Aston, Anthony Liguori
Jul 23, 2014·Forensic Science International : Synergy·Laís Helena Picolo BuenoBruno Spinosa De Martinis
Jul 22, 2017·Perceptual and Motor Skills·Helen Z WuJames J Grady
May 9, 2009·Analytical Chemistry·T A BrettellJ R Almirall

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