A Controlled Study on Efficacy and Egg Reappearance Period of Ivermectin in Donkeys Naturally Infected with Small Strongyles

Helminthologia
R A PapiniM Sgorbini

Abstract

The aim of the present study was to investigate the efficacy and the egg reappearance period (ERP) of ivermectin (IVM) in donkeys during a 13-week period. The study involved a total of 14 adult Amiata breed donkeys, 7 - 13 years of age, and naturally infected with small strongyles. A group of 10 donkeys was treated with IVM oral paste at a dose rate of 200 mcg/kg BW. Another group of 4 donkeys was kept as untreated control group. Faecal samples were collected and examined for strongyle eggs on day 0 before treatment. IVM efficacy was based on the faecal egg count reduction test (FECRT) on day 14 post-treatment. Then individual faecal samples were collected and examined by FECRT at weekly intervals. A FECRT of 100 % was found after treatment with IVM and its ERP, defined as the week when the mean FECRT decreased until to become lower than 90 %efficacy, was estimated to be 11 weeks without signs of developing anthelmintic resistance. No adverse reactions were observed during the study period. Our findings may be useful to veterinary practitioners and breeders as they show that IVM, at the recommended dose rate, can be still considered a highly effective and safe pharmacological tool for the treatment of small strongyles in donkey...Continue Reading

References

Aug 25, 2000·The Journal of Parasitology·S MattheeS A Milne
Jun 22, 2001·Journal of the American Veterinary Medical Association·J L Tarigo-MartinieR M Kaplan
May 21, 2003·Equine Veterinary Journal·D LittleS Y Gardner
Apr 11, 2009·Veterinary Parasitology·Sławomir KornaśBogusław Nowosad
Jun 24, 2009·Tropical Animal Health and Production·M GetachewS W J Reid
Oct 24, 2009·Veterinary Parasitology·M K NielsenR M Kaplan
Feb 2, 2010·Journal of the American Veterinary Medical Association·Dianne McFarlaneLara K Maxwell
Oct 15, 2011·Veterinary Parasitology·D C K van DoornH W Ploeger
Dec 1, 2008·Meat Science·P PolidoriD Beghelli
Jan 16, 2013·Veterinary Parasitology·Ricardo J CaneverMarcelo B Molento
Sep 23, 2014·Acta Parasitologica·Antonio BoscoGiuseppe Cringoli
Jan 13, 2015·Veterinary Parasitology·Edwina LawsonHany M Elsheikha
Jun 13, 2015·Journal of Parasitic Diseases : Official Organ of the Indian Society for Parasitology·A OryanM Rajabloo
Jun 15, 2016·Journal of Pathogens·Ahmed Abdurhman IsmailAdam Dawoud Abakar
May 6, 2013·Foods·Paolo Polidori, Silvia Vincenzetti
Oct 21, 2017·International Journal for Parasitology·Jennifer L BellawMartin K Nielsen
Jan 27, 2018·Parasites & Vectors·Rebecca A MolenaCinzia Cantacessi
May 1, 2019·Parasites & Vectors·Muhammad A SaeedAbdul Jabbar

❮ Previous
Next ❯

Citations

Jul 3, 2021·Animals : an Open Access Journal From MDPI·Valentina VitaleMarilena Bazzano

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.