A controlled trial of different treatment regimens in patients with urinary tract infections after lower urinary tract surgery

Current Medical Research and Opinion
C M EvansA E Kulatilake

Abstract

One hundred and four patients who developed urinary tract infections after catheterization for acute retention of urine and surgery of the bladder or urethra were randomly allocated to four treatment groups. Analysis of the results in 65 patients showed that co-trimoxazole and 1 g cephradine administered twice daily for 1 week were successful in eradicating the urinary tract infections in 93% and 88% of the patients, respectively. The same dose of cephradine administered 4-times a day eradicated 64% of the infections. In patients for whom no treatment was given, the original infection did not clear in 65%. Escherichia coli and coagulase-negative staphylococci were the commonest infecting organisms. The in vitro sensitivity testing of antibiotics did not correlate well with the successful eradication of the infecting organism.

References

Nov 1, 1977·British Journal of Urology·B Richards, J R Bastable
Jan 1, 1975·Current Medical Research and Opinion·R A Low, T K Clarke
Feb 1, 1974·Journal of Clinical Pharmacology·A ZakiJ A Hubsher

Citations

Jan 1, 1993·The Prostate·J C Nickel, J W Costerton
Jan 1, 1997·International Urology and Nephrology·T A SerelM Kecelioğlu
Jan 1, 1995·International Urology and Nephrology·Y Evliyaoğlu, H Kumbur
Jun 27, 2002·Current Urology Reports·J M Potts, E O'Dougherty
Aug 1, 2002·Current Urology Reports·Jeannette M Potts
Jul 21, 2004·Current Urology Reports·Pamela L Schultz, Robert F Donnell
Jun 28, 2005·Current Urology Reports·Puneet Sindhwani, Christopher M Wilson
Dec 20, 1999·Seminars in Roentgenology·N F Wasserman
Apr 21, 2006·The Cochrane Database of Systematic Reviews·S PhippsJ N'Dow

Related Concepts

Velocef
Clinical Trials
Antibiotic Resistance, Microbial
Postoperative Complications
Trimpex
Urinary Tract
Urinary Tract Infection

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