A controlled trial of early versus delayed feeding following ligation in the control of acute esophageal variceal bleeding

Journal of the Chinese Medical Association : JCMA
Gin-Ho LoYao-Chun Hsu

Abstract

The impact of feeding after endoscopic treatment of gastroesophageal varices has rarely been thoroughly investigated. We conducted a controlled study to evaluate whether delayed feeding causes a reduced incidence of rebleeding on patients receiving emergency endoscopic therapy for bleeding gastroesophageal varices. Cirrhotic patients presenting with acute esophageal variceal bleeding were provided critical treatment through emergency endoscopic variceal ligation. After bleeding from the varices had been arrested, the eligible participants were randomized to two groups. The early-feeding group and the delayed-feeding group were asked to fast for 4 hours and 48 hours, respectively, after endoscopic therapy. The primary end points were initial hemostasis, very early rebleeding, and ulcer-bleeding rates. There were 36 patients enrolled in the early-feeding group and 34 patients in the delayed-feeding group. Both groups were comparable in baseline data. Initial hemostasis was achieved in 100% in both groups, and very early rebleeding was not encountered in either group. The incidence of adverse events was similar between both groups. The mean hospitalization days were 6.0 ± 2.4 days (range: 2-17 days) in the early-feeding group, and...Continue Reading

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Citations

Sep 12, 2015·Journal of the Chinese Medical Association : JCMA·Ming-Chih Hou
Nov 25, 2017·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Gin-Ho Lo, Thomas Reiberger
May 1, 2019·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Sandeep Singh SidhuSamarth Singh Sidhu
Sep 19, 2021·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Sheau Wen KanTung-Yao Tsai

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