A cost-effectiveness approach to the Norwegian follow-up programme in colorectal cancer

Annals of Oncology : Official Journal of the European Society for Medical Oncology
J Norum, J A Olsen

Abstract

Today, continued periodic follow-up of patients treated for colorectal cancer (CRC) seems often to be routine because of tradition, rather than its demonstrated value. Recently, the Norwegian Gastrointestinal Cancer Group (NGICG) has recommended a standard surveillance programme in this malignancy. In this protocol patients are suggested followed for four years with CEA monitoring, ultrasound of the liver, chest radiograph and colonoscopy at regular intervals. In this study, the cost-effectiveness of this programme was addressed employing Norwegian cost data and data from the Cancer Registry of Norway. Clinical data from the existing English language literature was used in the analysis. The basic cost of the NGICG recommended programme was 1,232 Pounds per patient. Including extended investigation due to suspected relapse in 45% of cases, the figure raised to 1,943 Pounds per patient. The cost per life year saved was indicated to 9,525 Pounds-16,192 Pounds. The corresponding cost per quality adjusted life year (QALY) was indicated to 11,476 Pounds-19,508 Pounds. We conclude the NGICG recommended follow-up programme in CRC cost-effective. Excluding CEA monitoring may improve the cost-effectiveness.

Citations

Mar 10, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ian ChauJacqui Oates
May 29, 2004·European Journal of Gastroenterology & Hepatology·Paul Moayyedi, James Mason
Oct 1, 2008·Expert Review of Pharmacoeconomics & Outcomes Research·Jessica Corner
Aug 28, 2014·Annals of Surgical Oncology·Vanessa CottetAnne-Marie Bouvier
Sep 14, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C C EarleP J Neumann
Jan 17, 2004·ANZ Journal of Surgery·Daniel R McGrathAllan D Spigelman
Apr 12, 2008·Magyar onkologia·Félix SzentpéteryFerenc Jakab
Sep 17, 2015·Journal of Oncology Practice·Melissa K AccordinoDawn L Hershman
Jan 13, 2016·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·C J VerberneK M Vermeulen
Jan 17, 2004·ANZ Journal of Surgery·Tim R WorthingtonRobert Padbury
Aug 8, 2006·Surgical Oncology·Giovanni Li DestriStefano Puleo

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