A cost-utility analysis of microwave and thermal balloon endometrial ablation techniques for the treatment of heavy menstrual bleeding

BJOG : an International Journal of Obstetrics and Gynaecology
Ruth GarsideMartin Pitt

Abstract

To assess the cost effectiveness of the second-generation surgical treatments for heavy menstrual bleeding (microwave and thermal balloon endometrial ablation) compared with existing endometrial ablation techniques (transcervical resection and rollerball, alone or in combination) and hysterectomy. A state transition (Markov) cost-utility economic model. Women with heavy menstrual bleeding. A Markov model was developed using spreadsheet software. Transition probabilities, costs and quality of life data were obtained from a systematic review of effectiveness undertaken by the authors, from published sources, and expert opinion. Cost data were obtained from the literature and from a NHS trust hospital. Indirect comparison of thermal balloon endometrial ablation versus microwave endometrial ablation or either second-generation endometrial ablation method versus hysterectomy, and comparison of second-generation versus first-generation techniques were carried out from the perspective of health service payers. The effects of uncertainty were explored through extensive one-way sensitivity analyses and Monte Carlo simulation. Incremental cost effectiveness ratios based on cost per quality adjusted life year (QALY) gained, and cost effec...Continue Reading

References

Jan 1, 1987·Journal of Chronic Diseases·G W Torrance
Aug 1, 1995·British Journal of Obstetrics and Gynaecology·A ClarkeK Howle
Dec 29, 2000·Drug and Therapeutics Bulletin
Apr 13, 2002·BJOG : an International Journal of Obstetrics and Gynaecology·M J A MareshA Casbard
Apr 18, 2002·The Journal of the American Association of Gynecologic Laparoscopists·Erin MacLean-FraserGeorge A Vilos

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Citations

Sep 7, 2007·Archives of Gynecology and Obstetrics·C IavazzoA Liapis
Feb 20, 2009·Archives of Gynecology and Obstetrics·Chendrimada K MadhuTahira Naeem
Nov 4, 2010·Archives of Gynecology and Obstetrics·Adel Saad HelalLotfy Sherif
Jun 24, 2006·Current Opinion in Obstetrics & Gynecology·Nazar N Amso
Nov 4, 2006·Clinical Obstetrics and Gynecology·Malcolm G Munro
Jun 19, 2013·Current Opinion in Obstetrics & Gynecology·Jane P Daniels
May 22, 2007·Clinical Obstetrics and Gynecology·Malcolm G Munro
Nov 30, 2006·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·S S SadoonP Kirwan
Mar 6, 2012·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Sari AhonkallioHannu Martikainen
Apr 22, 2011·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Zahra AsgariSomayeh Sabet
Oct 19, 2010·European Journal of Obstetrics, Gynecology, and Reproductive Biology·I LeteM Brosa
May 26, 2007·Best Practice & Research. Clinical Obstetrics & Gynaecology·Paul McGurgan, Peter O'Donovan
Mar 21, 2007·Journal of Minimally Invasive Gynecology·Stephen Robson, Bronwyn Devine
Jun 22, 2013·BJOG : an International Journal of Obstetrics and Gynaecology·L Bansi-MatharuD A Cromwell
Mar 13, 2008·BJOG : an International Journal of Obstetrics and Gynaecology·H ZowallL Regan
Jul 30, 2010·The Journal of Obstetrics and Gynaecology Research·Saeed Mohamed Ahmad Thabet
May 30, 2006·Best Practice & Research. Clinical Obstetrics & Gynaecology·Ritva Hurskainen
Aug 5, 2015·Health Technology Assessment : HTA·T Justin ClarkJane P Daniels
Dec 15, 2010·American Journal of Obstetrics and Gynecology·Julia KopeikaMohamed A Hefni
Jun 25, 2005·Current Opinion in Obstetrics & Gynecology·Malcolm G Munro
Nov 30, 2013·The Cochrane Database of Systematic Reviews·Rosalie J FergussonCindy Farquhar
Aug 30, 2019·The Cochrane Database of Systematic Reviews·Rosalie J FergussonCindy Farquhar
Aug 11, 2017·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Michelle LouieJanelle K Moulder
Feb 24, 2021·The Cochrane Database of Systematic Reviews·Magdalena Bofill RodriguezRosalie J Fergusson
Jul 11, 2021·BJOG : an International Journal of Obstetrics and Gynaecology·M J van den BrinkM Y Berger

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