A critical appraisal of nutritional intervention studies in malnourished, community dwelling older persons

Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition
M A E de van der SchuerenM Visser

Abstract

With the rapidly increasing number of malnourished older persons in the community, this review aims to summarize the effects of nutritional intervention studies for this target group. Based on 2 previous reviews (2009, 2011) an update of the literature was performed. Selected were higher quality studies which included malnourished community dwelling older adults who received dietetic counselling and/or oral nutritional supplements. Ten studies were included. Six studies showed (trends towards) weight gain. Meta-analysis showed a modest effect of the intervention on weight gain, standardized mean difference 0.210 kg (95% CI 0.03-0.40). Effects on other relevant functional and clinical outcomes were inconsistent. Studies were hampered by low sample sizes, low adherence to the interventions, and participants not meeting nutritional requirements. Currently, nutritional intervention studies for malnourished community dwelling older adults show limited effects, which may be caused by methodological shortcomings and participants not meeting treatment goals. High quality studies are eagerly awaited to be able to identify (sub)groups of older persons who are most likely to benefit from nutritional support.

References

May 31, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·L Z RubensteinB Vellas
Aug 7, 2004·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Jan TidermarkTommy Cederholm
Feb 6, 2007·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Margareta PerssonTommy Cederholm
Nov 21, 2009·Journal of the American Geriatrics Society·Marion E T McMurdoDavid J Stott
Oct 13, 2010·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Juliane StarkeRémy Meier
Apr 30, 2011·Journal of the American Medical Directors Association·Floor NeelemaatMarian A E van Bokhorst-de van der Schueren
Sep 1, 2011·Alzheimer Disease and Associated Disorders·Odete Luísa Vicente de Sousa, Teresa F Amaral
Nov 1, 2011·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·José J L Breedveld-PetersPieter C Dagnelie
Nov 11, 2011·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Floor NeelemaatMarian A E van Bokhorst-de van der Schueren
Nov 22, 2011·Journal of Nutrition in Gerontology and Geriatrics·Julie L LocherKristin S Vickers
Feb 10, 2012·Journal of the American Geriatrics Society·Floor NeelemaatMarian A E van Bokhorst-de van der Schueren
May 7, 2013·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·R AnbarP Singer

❮ Previous
Next ❯

Citations

Nov 28, 2017·The Proceedings of the Nutrition Society·Sian M Robinson
Feb 9, 2018·The Proceedings of the Nutrition Society·Anne Marie Beck
Aug 24, 2018·Drug and Therapeutics Bulletin
Aug 3, 2018·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Dolores Sánchez-RodríguezEster Marco
Nov 15, 2019·Journal of Palliative Care·Erika BerggrenLena Törnkvist
Oct 21, 2020·Journal of Nutrition in Gerontology and Geriatrics·Anne Marie BeckChristine Baldwin
Jan 11, 2021·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Patricia Dominguez CastroClare A Corish
Dec 4, 2020·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Samuel Teong Huang ChewSiew Ling Tey

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.