A critical decrease in dominant frequency and clinical outcome after catheter ablation of persistent atrial fibrillation

Heart Rhythm : the Official Journal of the Heart Rhythm Society
Kentaro YoshidaHakan Oral

Abstract

Termination of persistent atrial fibrillation (AF) by radiofrequency ablation (RFA) is associated with a high probability of freedom from AF but requires extensive ablation and long procedure times. The purpose of this study was to determine whether a critical decrease in the dominant frequency (DF) of AF is a sufficient endpoint for RFA of persistent AF. Antral pulmonary vein isolation (APVI) followed by RFA of complex fractionated atrial electrograms (CFAEs) in the atria and coronary sinus was performed in 100 consecutive patients with persistent AF. The DF of AF in lead V1 and in the coronary sinus was determined by fast Fourier transform (FFT) analysis at baseline and before termination of AF to identify a critical decrease in DF predictive of sinus rhythm after RFA. A > or =11% decrease in DF had the highest accuracy in predicting freedom from atrial arrhythmias, with a sensitivity of 0.71 and a specificity of 0.82 (P <.001). At a mean follow-up of 14 +/- 3 months after one ablation procedure, sinus rhythm was maintained off antiarrhythmic drugs in 8/35 (23%) and 20/26 (77%) of patients with a <11% and > or =11% decrease in DF, respectively (P <.001). Sinus rhythm was maintained in 24/39 patients (62%) in whom RFA terminat...Continue Reading

References

Jul 26, 2002·Journal of Cardiovascular Electrophysiology·Hakan OralFred Morady
Mar 20, 2004·Journal of Cardiovascular Electrophysiology·Prashanthan SandersMichel Haïssaguerre
Sep 21, 2005·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Kristina LemolaHakan Oral
Nov 24, 2005·Journal of Cardiovascular Electrophysiology·Michel HaïssaguerrePierre Jaïs
Nov 24, 2005·Journal of Cardiovascular Electrophysiology·Michel HaïssaguerrePierre Jaïs
Dec 6, 2005·Journal of the American College of Cardiology·Eric GoodFred Morady
Jul 18, 2006·Journal of the American College of Cardiology·Kristina LemolaHakan Oral
Dec 17, 2008·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Claude S ElayiAndrea Natale
Jan 6, 2009·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Kentaro YoshidaHakan Oral

❮ Previous
Next ❯

Citations

Jun 15, 2011·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Kentaro YoshidaAman Chugh
Apr 10, 2013·Medical Engineering & Physics·Raúl AlcarazJosé Joaquín Rieta
Apr 14, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Iñaki RomeroCharalampos Kriatselis
Jun 30, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Jiun TuanG André Ng
Dec 21, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Shahriar IravanianJonathan J Langberg
Sep 8, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Shiro NakaharaKan Takayanagi
Jul 24, 2012·American Journal of Physiology. Heart and Circulatory Physiology·Jacob I LaughnerIgor R Efimov
Dec 3, 2013·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Shiro NakaharaKan Takayanagi
Jul 30, 2014·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Shiro NakaharaKan Takayanagi
Apr 16, 2014·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Kentaro YoshidaNoriyuki Takeyasu
Aug 2, 2014·Herzschrittmachertherapie & Elektrophysiologie·Kerstin BodeGerhard Hindricks
Dec 3, 2014·Cardiology Clinics·Omer Berenfeld, José Jalife
Dec 19, 2012·Expert Review of Cardiovascular Therapy·Jaimie ManlucuGregory F Michaud
May 28, 2011·Expert Review of Cardiovascular Therapy·Demosthenes G KatritsisEfstathios P Efstathopoulos
Apr 3, 2012·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Hamid Ghanbari, Hakan Oral
Jun 15, 2010·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Jérôme Kalifa
Feb 27, 2010·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Jonathan M Kalman, Andrew W Teh
Mar 13, 2016·Heart Failure Clinics·Omer Berenfeld, José Jalife
Dec 25, 2015·Journal of Arrhythmia·Kentaro YoshidaKazutaka Aonuma
Jun 19, 2013·Journal of Cardiovascular Electrophysiology·Thomas DenekeAndreas Mügge
Mar 21, 2012·Journal of Cardiovascular Electrophysiology·Yujiao ZhangYinglong Hou
Jun 28, 2011·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Andrei ForclazMichel Haïssaguerre
Dec 19, 2017·Journal of Atrial Fibrillation·Lucaz GadenzDamian P Redfearn
Sep 24, 2015·Physiological Measurement·Matilde JuliánJosé J Rieta
Apr 4, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Neal K BhatiaSanjiv M Narayan
Apr 5, 2012·Circulation Journal : Official Journal of the Japanese Circulation Society·Yoko SatoKazutaka Aonuma
Jan 1, 2011·Current Opinion in Cardiology

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antiarrhythmic Agents: Mechanisms of Action

Understanding the mechanism of action of antiarrhythmic agents is essential in developing new medications as treatment of cardiac arrhythmias is currently limited by the reduced availability of safe and effective drugs. Discover the latest research on Antiarrhythmic Agents: Mechanism of Action here.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Cardiac Conduction System

The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.

Anti-Arrhythmic Drug Therapies

Anti-arrhythmic drugs are used to prevent abnormal heart rhythms. These medications are used in conditions including, ventricular tachycardia, ventricular fibrillation and atrial fibrillation. Discover the latest research on anti-arrhythmic drug therapies here.