A cross-sectional survey to investigate the prevalence of pain in Japanese patients with major depressive disorder and schizophrenia

Comprehensive Psychiatry
Taro KishiNakao Iwata

Abstract

We conducted a cross-sectional survey to assess the prevalence of physical pain in Japanese major depressive disorder (MDD) and schizophrenia (SZ) patients as well as in healthy controls (HCs). We also examined the association between their psychopathology and characteristics of pain according to a face-to-face survey by an experienced psychiatrist and psychologist. We analyzed 233 HCs, 94 MDD patients, and 75 SZ patients using the McGill Pain Questionnaire (MPQ) and SF-8 (all participants), the Hamilton Depression Rating Scale 21 items (MDD patients), and the Positive and Negative Symptom Scale (SZ patients). Although MDD patients experienced more pain than HCs, there was no difference in the prevalence of pain between SZ patients and HCs. Moreover, HCs with pain did not have higher SF-8 total scores than those without pain, whereas both MDD and SZ patients with pain had higher SF-8 total scores than those without pain. The severity of psychopathology in MDD and SZ patients was also positively associated with both the prevalence of pain and MPQ scores. MPQ scores were also associated with positive symptoms in SZ patients. Considering these results, physicians need to query MDD patients about physical pain during examination if...Continue Reading

References

Jan 1, 1987·Schizophrenia Bulletin·S R KayL A Opler
Oct 28, 1999·The New England Journal of Medicine·G E SimonJ Ormel
Feb 1, 1960·Journal of Neurology, Neurosurgery, and Psychiatry·M HAMILTON
Jan 30, 2004·Psychosomatic Medicine·Matthew J BairKurt Kroenke
Feb 27, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Chiaki FukuharaGianluca Tosini
May 27, 2006·Journal of Psychiatric Practice·Manpreet K SinghHenry A Nasrallah
Nov 9, 2010·Journal of Affective Disorders·L Agüera-OrtizJ J López-Ibor
Jan 3, 2012·Comprehensive Psychiatry·Shinji ShimoderaToshi A Furukawa
May 23, 2013·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·John Peter NeySean D Sullivan
Jun 26, 2013·British Journal of Anaesthesia·E J Bartley, R B Fillingim
Nov 15, 2013·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Zachary McCormickR Norman Harden
Dec 25, 2013·The Journal of Pain : Official Journal of the American Pain Society·Gwenda EngelsErik J A Scherder

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Citations

Jun 23, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Hung-Yu HuangYi-Wen Lin
Nov 25, 2020·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Masashi SakuraiMasahiro Morimoto
Jun 8, 2021·Progress in Neuro-psychopharmacology & Biological Psychiatry·Zi-Han LiuYu-Tao Xiang

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