A cyclopean neural mechanism compensating for optical differences between the eyes

Current Biology : CB
Aiswaryah RadhakrishnanSusana Marcos

Abstract

The two eyes of an individual routinely differ in their optical and neural properties, yet percepts through either eye remain more similar than predicted by these differences. Little is known as to how the brain resolves this conflicting information. Differences in visual inputs from the two eyes have been studied extensively in the context of binocular vision and rivalry [1], but it remains unknown how the visual system calibrates and corrects for normal variability in image quality between the eyes, and whether this correction is applied to each eye separately or after their signals have converged. To test this, we used adaptive optics to control and manipulate the blur projected on each retina, and then compared judgments of image focus through either eye and how these judgments were biased by adapting to different levels of blur. Despite significant interocular differences in the magnitude of optical blur, the blur level that appeared best focused was the same through both eyes, and corresponded to the ocular blur of the less aberrated eye. Moreover, for both eyes, blur aftereffects depended on whether the adapting blur was stronger or weaker than the native blur of the better eye, with no aftereffect when the blur equaled ...Continue Reading

References

Oct 1, 1987·American Journal of Optometry and Physiological Optics·C SchorP Erickson
Aug 27, 2002·Nature Neuroscience·Michael A WebsterShernaaz M Webster
Aug 10, 2007·Journal of Vision·Derek H ArnoldThomas S A Wallis
Nov 14, 2007·Journal of Vision·Mark A GeorgesonGillian S Hesse
Nov 4, 2008·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Michael A Webster, Deanne Leonard
Oct 19, 2010·Vision Research·Randolph Blake, Hugh Wilson
May 24, 2011·Journal of Vision·Michael A Webster

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Citations

Feb 10, 2016·Annual Review of Vision Science·Michael A Webster
Feb 19, 2017·Vision Research·Susana MarcosLawrence C Sincich
Feb 6, 2018·Cognitive Research: Principles and Implications·Elysse Kompaniez-DuniganMichael A Webster
Mar 10, 2020·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Susana MarcosMaria Vinas
Jan 1, 2017·Vision·Kevin C DieterRandolph Blake
Oct 2, 2020·Scientific Reports·Victor Rodriguez-LopezJohannes Burge
May 14, 2020·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Michael A Webster
Feb 27, 2021·Vision Research·Kara J EmeryMichael A Webster
Jan 5, 2022·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Gareth D HastingsJason D Marsack

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