A cytochemical study of the localization of acid phosphatase in Saccharomyces cerevisiae at different growth phases

The Histochemical Journal
E I RaininaV N Luzikov


The localization of acid phosphatase in the yeast Saccharomyces cerevisiae at different growth phases had been studied. It was shown to be crucial for authentic location of acid phosphatase that the cytochemical reaction be performed on whole cells. Dimethylsulphoxide was used to alleviate the effects of fixation of the yeast cells with glutaraldehyde; the sulphoxide did not affect the distribution of acid phosphatase in the cells. It has been established that in exponentially-growing cells acid phosphatase is localized mostly in small vacuolar compartments. In mature cells, the bulk of acid phosphatase is found in the central vacuole, although a significant amount of the enzyme is detectable in the plasma membrane and the adjacent vesicles.


Mar 28, 1975·Biochimica Et Biophysica Acta·T Saheki, H Holzer
Sep 1, 1975·Journal of Bacteriology·H J Van RijnP Boer
Feb 1, 1975·Journal of Ultrastructure Research·H Bauer, E Sigarlakie
Jul 1, 1974·Experimental Cell Research·F V Hereward
Oct 23, 1974·Biochemical and Biophysical Research Communications·J F LenneyJ Meyer
Oct 26, 1973·Histochemie. Histochemistry. Histochimie·D W Misch, M S Misch
Feb 20, 1967·Archiv für Mikrobiologie·P Matile, A Wiemken
Jan 1, 1966·Annual Review of Physiology·C De Duve, R Wattiaux
Dec 17, 1958·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·A A EDDY

Related Concepts

Acid Phosphatase
Hydrogen-Ion Concentration
Electron Microscopy
Saccharomyces cerevisiae
Subcellular Fractions

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Synthetic Genetic Array Analysis

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Congenital Hyperinsulinism

Congenital hyperinsulinism is caused by genetic mutations resulting in excess insulin secretion from beta cells of the pancreas. Here is the latest research.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Epigenetic Memory

Epigenetic memory refers to the heritable genetic changes that are not explained by the DNA sequence. Find the latest research on epigenetic memory here.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Femoral Neoplasms

Femoral Neoplasms are bone tumors that arise in the femur. Discover the latest research on femoral neoplasms here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.