A daily diary study of late-life depression

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
Lara G ChepenikIra R Katz

Abstract

The objective of this study was to use data from daily diaries to characterize the day-to-day variability in positive and negative affects, and the relationship between daily events and daily affects in primary care patients with late-life depression. Daily diary data were obtained from primary care patients with major depression (N = 25) and other depressive disorders (N = 33); data from a two-week period were compared with those from elderly normal volunteer comparison subjects (N = 70) who participated in other studies. There was significant day-to-day variability in negative affect in patients with major depression and other depressive disorders. Dysphoric days (days with a negative affect ratings that occurred once every two weeks in normal subjects) represented 65.3% (standard deviation [SD]: 37.1) of days in those with major depression and 50.6% (SD: 37.6) in those with other depression versus 7.7% (SD: 16.3) in normal subjects (F = 36.0, p <0.001). The groups did not differ significantly in the number of positive and negative events reported, but the proportion of dysphoric days that occurred in association with negative events was greater in normal subjects than in those with major depression. Mixed-effects analyses de...Continue Reading

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Citations

Mar 11, 2009·Journal of Psychiatric Research·Ashley E CainDilip V Jeste
Jul 9, 2008·Contemporary Clinical Trials·William R LenderkingA John Rush
Nov 28, 2008·International Journal of Methods in Psychiatric Research·Ronald C KesslerAlan M Zaslavsky
Feb 11, 2015·International Journal of Neurology and Neurotherapy·Michael F ArmeyIvan W Miller
May 2, 2016·Journal of Affective Disorders·Rachel Pemberton, Matthew D Fuller Tyszkiewicz
Jun 2, 2011·The Journal of Nervous and Mental Disease·Leslie H BrownThomas R Kwapil
Jul 7, 2021·Experimental Neurology·Markus ReichertAndreas Meyer-Lindenberg

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