A descriptive report of the effects of a 16-month xylitol chewing-gum programme subsequent to a 40-month sucrose gum programme

Caries Research
K K MäkinenP L Mäkinen

Abstract

A previous caries trial (Belize studies) involved the usage of sucrose chewing-gum for a period of 40 months in one group of initially 10-year-old subjects in an environment of high sugar consumption, high caries activity, and limited access to restorative care. After the termination of the 40-month supervised sucrose gum usage, the 109 subjects of the original sucrose group retrieved at the endpoint of the original trial were invited to participate in a xylitol chewing-gum programme (involving the usage of the '100% pellet-shaped formular') for 16 months. The average daily consumption level of xylitol was up to 14 g per subject, normally used in seven daily chewing episodes. Although most subjects used chewing-gum at schools and received their gum portions from a school official, gum chewing during these 16 months was mostly unsupervised. After 16 months, 83 subjects (76%; mean age 14.9 years) were retrieved. The caries status of these subjects was examined by the same calibrated, blinded examiners as in the original trial. To mask the examiners, 141 similar non-participating subjects were recruited from the same school classes and were examined in a random order with the gum-using subjects, according to the same standard rout...Continue Reading

Citations

Dec 20, 2013·Journal of the American Chemical Society·Jing ChenLai-Sheng Wang
Mar 27, 2010·International Journal of Dentistry·Kauko K Mäkinen
May 18, 2011·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·Kauko K Mäkinen
May 3, 2008·The Journal of the American Dental Association·Kiet A LyMarilynn Rothen
Mar 29, 2006·Journal of Dental Research·P P HujoelW J Loesche
Mar 29, 2006·Journal of Dental Research·J M TanzerR A Burne
Aug 28, 2009·Advances in Dental Research·P MilgromM Rothen
Sep 1, 2009·Advances in Dental Research·E M Söderling
Nov 20, 2019·JDR Clinical and Translational Research·J T NewtonA Banerjee
Jan 1, 2012·The Journal of Clinical Pediatric Dentistry·Najlaa M AlamoudiDouaa A El Derwi
Nov 20, 2002·Dental Clinics of North America·Erik ScheifeleNina Markovic

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