A descriptive study of the relationship between mood disorders and hepatitis C treatment compliance: does nursing play a role?

Issues in Mental Health Nursing
Janice M StrinkoJoyce A Hoffmann

Abstract

Chronic hepatitis C is a common and often serious condition. Current treatment uses antiviral therapy based on alpha interferon. Neuropsychiatric side effects are common with interferon therapy, and the management of mood disorders during treatment for hepatitis C is an important part of helping patients maintain compliance, thus improving their chance of having a successful treatment outcome. This descriptive study examined the incidence of mood disorders in 29 treatment naïve patients with chronic hepatitis C participating in a clinical trial of various interferon-based therapies. Relationships among mood disorders, use of antidepressants, hepatitis treatment compliance, and sustained treatment response (having undetectable hepatitis C viral load 24 weeks post-treatment) were examined. Eighty-one percent of sustained responders experienced psychiatric events, and it is speculated that comprehensive nursing support and intervention were key components in achieving favorable patient outcomes.

References

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Citations

Jan 24, 2013·The Journal of the Association of Nurses in AIDS Care : JANAC·Gillian Farrell, Catherine Comiskey
May 26, 2007·Journal of Advanced Nursing·Max Hopwood, Carla Treloar
Mar 2, 2006·Psychosomatics·Muhamad Aly RifaiBrian J Van der Linden
Aug 7, 2008·Journal of Hepatology·Beate LettmeierUwe Siebert
Nov 30, 2018·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Sheila A Williams
Oct 3, 2018·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Sheila Williams

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