A design improvement strategy for axial blood pumps using computational fluid dynamics

ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs
G W BurgreenB P Griffith

Abstract

During the initial stages of concept development of non traditional axial flow pumps, numeric simulation offers an attractive advantage. Computational fluid dynamics (CFD) provides the rationale to evolve the design numerically such that undesirable flow features may be significantly mitigated before a physical prototype is fabricated. The initial design of a novel axial flow blood pump is shown through CFD analysis to exhibit large regions of reverse flow. Such fluid dynamic behavior not only decreases the pump's hydrodynamic efficiency, but, more significantly, increases its overall potential for blood trauma and thrombogenesis. The design improvement strategy consists of creating a geometric model of the blood wetted surfaces and changing the associated geometric parameters such that more desirable fluid dynamic behavior is systematically attained with each incremental modification. The fluid flow through each new pump design is analyzed by numerically solving the incompressible Navier-Stokes equations in rotating coordinates. Marked improvements in the major fluid dynamic aspects of the axial flow pump were observed over an evolutionary sequence of four generations of pump design.

Citations

Feb 5, 2010·Annals of Biomedical Engineering·D BluesteinK B Manning
Mar 27, 2001·The Annals of Thoracic Surgery·B P GriffithK C Butler
Jan 9, 2014·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Wei-Che ChiuDanny Bluestein
Feb 17, 2000·Artificial Organs·M J GartnerW R Wagner
Jun 14, 2001·Artificial Organs·G W BurgreenA J Holmes
Nov 21, 2007·The Journal of Thoracic and Cardiovascular Surgery·Michael MarklFriedhelm Beyersdorf
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May 29, 2016·Medical & Biological Engineering & Computing·Erfan NammakieFarzan Ghalichi
Sep 25, 2009·Artificial Organs·Fangjun ShuJames F Antaki
Oct 26, 2018·The International Journal of Artificial Organs·Matteo SelmiFilippo Consolo
Dec 3, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·David H J WangJames A Magovern
Mar 7, 2006·Expert Review of Medical Devices·Katsuhiro Ohuchi, Setsuo Takatani

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