A deviant genetic code in the reduced mitochondrial genome of the picoplanktonic green alga Pycnococcus provasolii.

Journal of Molecular Evolution
Monique TurmelClaude Lemieux

Abstract

Reduction in size of flagellated chlorophytes occurred multiple times during evolution, providing the opportunity to study the consequences of cell reduction on genome architecture. Recent investigations on the chloroplast genomes of the tiny prasinophyceans Ostreococcus tauri (Mamiellales), Micromonas sp. RCC299 (Mamiellales), and Pycnococcus provasolii (Pseudocourfieldiales) highlighted their extreme compaction and reduced gene repertoires. Genome compaction is also exemplified by the Ostreococcus and Micromonas mitochondrial DNAs (mtDNAs) although they have retained almost all of the about 65 genes presumably present in the mitochondria of ancestral prasinophyceans. In this study, the mitochondrial genome of Pycnococcus was sequenced and compared to those of previously examined chlorophytes. Our results document the first case where cellular reduction of a free-living alga was accompanied by marked reduction in gene content of both the mitochondrial and chloroplast genomes. At 24,321 bp, the intronless Pycnococcus mitochondrial genome falls within the lower size range displayed by green algal mtDNAs. The 36 conserved genes, specifying two rRNAs with conventional structures, 16 tRNAs and 18 proteins, are all encoded on the sa...Continue Reading

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Citations

Jun 25, 2010·Current Genetics·David Roy SmithRobert W Lee
Sep 21, 2013·Nucleic Acids Research·Jiqiang LingB Franz Lang
Mar 2, 2011·IEEE/ACM Transactions on Computational Biology and Bioinformatics·Harry BuhrmanLeen Stougie
Oct 25, 2016·The Journal of Eukaryotic Microbiology·Štěpánka HrdáVladimír Hampl
Jan 31, 2019·Molecular Biology and Evolution·Emmanuel NoutahiBernd Franz Lang
Oct 17, 2019·Genome Biology and Evolution·David Žihala, Marek Eliáš

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