PMID: 8580568Sep 1, 1995Paper

A dialysis patient with systemic calciphylaxis exhibiting rapidly progressive visceral ischemia and acral gangrene

Internal Medicine
M TamuraA Kuroiwa

Abstract

Systemic calciphylaxis is a rare, poorly understood syndrome of progressive peripheral ischemic necrosis and medial arterial calcification in patients with end-stage renal disease. We report a patient with this syndrome which developed following corticosteroid administration and who ultimately required amputation of the four extremities. Furthermore, cerebral, myocardial, splenic, and intestinal infarctions also developed in parallel with the increment of visceral arterial calcification. No evidence of noticeable hyperparathyroidism or elevation of serum calcium-phosphate product was observed. We speculated that, in addition to diabetes mellitus and chronic renal failure while undergoing dialysis therapy, the administration of corticosteroids might act synergistically to cause calciphylaxis.

Citations

Sep 1, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Abubakr A ImamRudolph P Valentini
Feb 23, 2011·Seminars in Dialysis·Kaelin Volpini, Chris Kinonen
Jul 11, 2013·Case Reports in Urology·Vincenzo BarberaAlberto Santoboni
Mar 29, 2001·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·W A WilmerF G Cosio
Nov 16, 2012·Renal Failure·Ayse Serap YalinMelike Melikoglu
Jun 3, 2009·Ugeskrift for laeger·Mette Wanscher KjaerskovKnud Bonnet Yderstraede
Oct 31, 1998·Vascular Medicine·S M Dean, H Werman
Jan 20, 2000·Muscle & Nerve·D P RandallC Thomas
Jul 15, 2004·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·H HassaballaR A Prinz
Jul 9, 2002·Seminars in Dialysis·William A Wilmer, Cynthia M Magro
Feb 8, 2002·Gastroenterology·Jesús Rivera-NievesFabio Cominelli
Mar 31, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·D T JaniganA S MacDonald

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