A diffuse reflectance spectroscopic study of UV-induced erythematous reaction across well-defined borders in human skin

Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
Erik HäggbladE Göran Salerud

Abstract

The colour of tissue is often of clinical use in the diagnosis of tissue homeostasis and physiological responses to various stimuli. Determining tissue colour changes and borders, however, often poses an intricate problem and visual examination, constituting clinical praxis, does not allow them to be objectively characterized or quantified. Demands for increased inter- and intra-observer reproducibility have been incentives for the introduction of objective methods and techniques for tissue colour (e.g. erythema) evaluation. The aim of the present paper was to study the border zone of a UVB-provoked erythematous response of human skin in terms of blood volume and oxygenation measured by means of diffuse reflectance spectroscopy using a commercial probe. A provocation model, based on partial masking of irradiated skin areas, defines two erythema edges at every skin site responding to the UV irradiation. In every subject, five test sites were exposed with a constant UV light irradiance (14 mW/cm(2)), but with different exposure times (0, 3, 6, 9 and 12 s). An analysis of the spectral data measured across the two edges was performed for every scan line. The oxygenized and deoxygenized haemoglobin contents were estimated in every m...Continue Reading

References

Apr 1, 1978·The British Journal of Dermatology·A P Warin
Jul 1, 1985·The British Journal of Dermatology·P M Farr, B L Diffey
Aug 1, 1996·Photodermatology, Photoimmunology & Photomedicine·J Lock-Andersen, H C Wulf
Apr 9, 1998·IEEE Transactions on Medical Imaging·M Nischik, C Forster
Feb 13, 2001·The Journal of Investigative Dermatology·L M McIntoshJ W Toole
Feb 24, 2001·Medical & Biological Engineering & Computing·I V Meglinsky, S J Matcher
Oct 27, 2001·Microvascular Research·E HäggbladE G Salerud
Jul 31, 2002·Photodermatology, Photoimmunology & Photomedicine·Herbert Hönigsmann
Sep 19, 2002·International Journal of Cancer. Journal International Du Cancer·Pietro RubegniLucio Andreassi
Jan 1, 2003·Computer Methods and Programs in Biomedicine·I V Meglinski, S J Matcher
Aug 20, 2003·Photodermatology, Photoimmunology & Photomedicine·Magnus FalkChris Anderson
Jan 21, 2004·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·M A IliasE G Salerud
Mar 9, 2006·Photochemistry and Photobiology·Sergio G CoelhoJanusz Z Beer
Jul 29, 2006·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Ki-Hong KimJong-Ki Kim
Mar 5, 2008·Journal of Biomedical Optics·Ingemar FredrikssonTomas Strömberg
Jul 23, 2008·Photochemistry and Photobiology·Merve MeinhardtHagen Tronnier
Oct 22, 2008·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·M FalkC Anderson
Nov 22, 2008·Journal of Biomedical Optics·Merve MeinhardtHagen Tronnier

❮ Previous
Next ❯

Citations

Jan 5, 2011·Photodermatology, Photoimmunology & Photomedicine·Zain U Syed, Iltefat H Hamzavi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.