Abstract
HIV-associated prospective memory (ProM) impairment has emerged, in earlier studies as a significant predictor of medication management and independence in activities of daily living. The relationship between ProM and white matter integrity in HIV has not previously been investigated. Participants, including 128 HIV-infected individuals and 32 healthy controls, were assessed using a comprehensive neuropsychological evaluation and both objective and subjective measures of ProM. Diffusion tensor imaging (DTI) was utilized to investigate the relationship of white matter integrity to ProM in a randomly selected subsample of 40 HIV positive subjects, using a whole brain voxel-based approach to define fractional anisotrophy (FA) and mean diffusion (MD). Total prospective memory was significantly poorer in the HIV positive group when compared with healthy controls (p = 0.023). Time-based ProM was poorer in the HIV group compared to healthy controls both without prompts (p = 0.001) and with prompts (p = 0.001). Poor Total ProM score correlated with performance on neuropsychological tests of executive functioning, information processing speed, learning, and working memory (p < 0.05). Those HIV positive participants with poor ProM had si...Continue Reading
References
Feb 1, 1982·The British Journal of Clinical Psychology·D E BroadbentK R Parkes
Nov 1, 1995·Psychological Medicine·J C StoutJ L Chandler
Nov 1, 1995·NMR in Biomedicine·P J Basser
Apr 1, 1996·Journal of Clinical and Experimental Neuropsychology·J Cockburn
Oct 17, 1998·Neuroscience Letters·J OkudaH Fukuda
Jun 22, 2000·NeuroImage·J Ashburner, K J Friston
Mar 7, 2001·Psychiatry Research·N PomaraK O Lim
Mar 21, 2001·Neuropsychologia·P W BurgessC D Frith
Apr 2, 2003·Neuropsychologia·Paul W BurgessChristopher D Frith
Aug 12, 2003·Memory·John R CrawfordRobert H Logie
Jun 21, 2005·NeuroImage·H E M den OudenS-J Blakemore
Jul 23, 2005·Journal of Neurovirology·Ann B RaginLeon G Epstein
Mar 4, 2006·Neuropsychologia·Jon S SimonsPaul W Burgess
Apr 21, 2006·NeuroImage·Stephen M SmithTimothy E J Behrens
May 9, 2006·Journal of Clinical and Experimental Neuropsychology·Catherine L CareyUNKNOWN HIV Neurobehavioral Research Center (HNRC) Group
Dec 13, 2006·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Steven Paul WoodsUNKNOWN HIV Neurobehavioral Research Center (HNRC) Group
Feb 10, 2007·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Steven Paul WoodsUNKNOWN HIV Neurobehavioral Research Center (HNRC) Group
Feb 5, 2008·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Steven Paul WoodsUNKNOWN HIV Neurobehavioral Research Center Group
Mar 24, 2009·Journal of Neurovirology·Assawin GongvatanaUNKNOWN Charter Group
Aug 4, 2009·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Christopher ContardoMarc I Rosen
Aug 15, 2009·AIDS Research and Human Retroviruses·Lucy J GarveyAlan Winston
Jul 28, 2010·The Clinical Neuropsychologist·Jennifer B ZoggUNKNOWN HIV Neurobehavioral Research Center Group
Nov 26, 2010·Neuropsychology·Sarah A RaskinAlexander I Tröster
Citations
Nov 8, 2017·Brain Imaging and Behavior·Jodi M Heaps-WoodruffRobert H Paul
Dec 17, 2014·Tropical Medicine & International Health : TM & IH·Lena Morgon BanksHannah Kuper
Sep 25, 2014·Current Opinion in HIV and AIDS·Beau M Ances, Dima A Hammoud
Aug 4, 2016·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Virawudh SoontornniyomkijUNKNOWN Translational Methamphetamine AIDS Research Center (TMARC) Group
May 16, 2017·Frontiers in Human Neuroscience·Sharif I KronemerCherie L Marvel
Sep 28, 2017·The Clinical Neuropsychologist·Gunes AvciSteven Paul Woods
Sep 19, 2018·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Huajun LiangThomas Ernst
Aug 21, 2020·Scientific Reports·Georgette D KanmogneRobert K Heaton
Nov 13, 2015·Neurology·Sophie CohenDasja Pajkrt
Sep 20, 2015·Journal of the International AIDS Society·Olurotimi A AdejumoBabafemi O Taiwo
Oct 2, 2015·BMC Research Notes·Victor M TangAlasdair M Barr
Nov 11, 2015·The Clinical Neuropsychologist·Jade A WittenJohn A Joska
Dec 23, 2015·AIDS·Tanja SuUNKNOWN AGEhIV Cohort Study
Nov 25, 2020·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Karen Cilliers, Christo J F Muller
Nov 10, 2020·Frontiers in Immunology·Michellie ThurmanSiddappa N Byrareddy
Aug 28, 2020·BMJ Open·J Cobb ScottElizabeth D Lowenthal
Aug 25, 2021·Current HIV/AIDS Reports·Susmita SilShilpa Buch
Sep 24, 2021·Journal of Neurovirology·Alexandra HaddadMark W Burke
Aug 30, 2019·Dementia and Geriatric Cognitive Disorders·Yen-Hsuan HsuMin-Chien Tu