PMID: 6976614Jan 1, 1981Paper

A digital quantitative method of estimating inflammation in the rectal mucosa. I. The normal limits in asymptomatic patients

Scandinavian Journal of Gastroenterology
C A Rubio, Y Kock

Abstract

Histological preparations of the rectal mucosa from 72 rheumatic patients without gastrointestinal symptoms were quantitatively analysed. The variables recorded were the diameter (minor axis) of ten consecutive transversally cut glands, the space of lamina propria between the glands, the number of glands per high-power field, and the number of nuclei in ten consecutive areas (of lamina propria) between the glands. The digitals resulting from the sum of the values in each variable were considered characteristic of the histological state of the rectal mucosa in individual patients. In most biopsies (i.e. 99%) scores of 21 or less were recorded. The data obtained serve as a basis for comparative studies of the histological state of the rectal mucosa from patients with various chronic inflammatory conditions of the rectum.

References

Jun 1, 1976·The American Journal of Digestive Diseases·B I Korelitz, S C Sommers
Mar 1, 1975·American Journal of Clinical Pathology·S C Sommers, B I Korelitz
Dec 28, 1972·The New England Journal of Medicine·B C Morson
Sep 1, 1972·Human Pathology·S Eidelman, D Lagunoff
Oct 1, 1960·The American Journal of Digestive Diseases·G LUMB

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