A Digital Squamous Cell Carcinoma Mimicking a Diabetic Foot Ulcer, With Early Inguinal Metastasis and Cancer-Related Lymphedema

The American Journal of Dermatopathology
Hyun Chul ParkJoo Yeon Ko

Abstract

Although squamous cell carcinoma (SCC) is the second most common nonmelanoma skin cancer, clinicians have difficulty diagnosing SCC of the toe because its clinical features can mimic other less serious diseases. Clinicians are especially prone to misdiagnose SCC of the toe as diabetic foot ulcer in patients with diabetes mellitus because of the clinical similarity of the 2 ailments. SCC of the toe is generally considered to have a low risk of metastasis. Locoregional or distant metastases without bone or tendon involvement are particularly rare. The authors report here an interesting case of rapidly spreading SCC of the toe with metastasis to multiple lymph nodes and cancer-related lymphedema. Physicians should be aware of the possibility of malignancy when they encounter chronic and recalcitrant ulcerative lesions of the digits.

References

Oct 1, 1984·Journal of the American Academy of Dermatology·L R LumpkinJ A Tschen
Jul 21, 2005·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Kuo-Chin HuangYen-Yao Li
Feb 1, 2007·The British Journal of Dermatology·S DalleL Thomas

❮ Previous
Next ❯

Citations

Jun 10, 2020·IUBMB Life·Rasoul MirzaeiRasoul Yousefimashouf
Dec 24, 2017·The Journal of Investigative Dermatology·Horacio A RamirezMarjana Tomic-Canic
Oct 30, 2021·International Wound Journal·Alexey V LyundupIlya D Klabukov

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Related Papers

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]
Kuo-Chin HuangYen-Yao Li
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Gary L ClaymanScott M Lippman
Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]
Hiroshi FurukawaTsuneki Sugihara
© 2021 Meta ULC. All rights reserved