A discordant monozygotic-twin approach to potential risk factors for chronic widespread pain in females

Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies
Andrea BurriFrances Williams

Abstract

Chronic widespread pain (CWP) is a common disorder affecting up to 15% of the general population. The objective of the present study was to explore the role of previously reported psychosocial and interpersonal risk factors on variation in CWP by investigating CWP discordant monozygotic (MZ) twins. This approach allows separation of cause and effect relationships, albeit imperfectly, as well the control for critical confounding variables such as common environment or genetics. In a total sample of N = 3,266 female twins aged 18-89 years, MZ (113 full pairs) and DZ twins (180 full pairs) discordant for CWP were selected. Items from the London fibromyalgia symptom screening questionnaire were used to discriminate cases from controls. To assess potential risk factors, including body mass index, anxiety sensitivity (AS), emotional intelligence, personality, obsessive-compulsive behavior, and coping, validated questionnaires were used. A set of univariate and multivariate logistic regression analyses were conducted. Of the variables showing significant links with CWP in the univariate individual-level analyses, including age, AS, and emotional intelligence, only emotional intelligence turned out to an independent predictor to the pa...Continue Reading

References

Nov 19, 1965·Science·R Melzack, P D Wall
Mar 1, 1994·The Clinical Journal of Pain·E Fernandez, T W Milburn
Sep 1, 1996·Journal of Personality·K L JangP A Vernon
Sep 1, 1996·Journal of Child Psychology and Psychiatry, and Allied Disciplines·A PikeR Plomin
May 1, 1997·Journal of Psychosomatic Research·R H AdlerS I Zlot
Dec 16, 1997·Clinical Psychology Review·K A Winter, N A Kuiper
Feb 11, 2000·Psychological Bulletin·E Turkheimer, M Waldron
Feb 13, 2001·Pain·M de Wied, M N Verbaten
Jan 10, 2002·Twin Research : the Official Journal of the International Society for Twin Studies·T AndrewA J MacGregor
Dec 28, 2002·Psychological Assessment·Edna B FoaPaul M Salkovskis
Jul 10, 2003·Best Practice & Research. Clinical Rheumatology·Daniel J Clauw, Leslie J Crofford
Oct 29, 2003·Pain·Chantal VillemureM Catherine Bushnell
Jun 3, 2004·Journal of Behavioral Medicine·Carmen Ramírez-MaestreRosa Esteve Zarazaga
Aug 9, 2005·The Journal of Pain : Official Journal of the American Pain Society·Michael E GeisserMichelle T Leonard
Jan 1, 1997·International Journal of Behavioral Medicine·C S Carver
Apr 29, 2006·Arthritis and Rheumatism·Kenji KatoNancy L Pedersen
May 6, 2006·The Spanish Journal of Psychology·Natalio Extremera, Pablo Fernández-Berrocal
May 16, 2006·Pain·Karen G RaphaelRollin M Gallagher
May 30, 2006·Journal of Psychosomatic Research·Urs M NaterChristine Heim
Jun 6, 2006·The Journal of Pain : Official Journal of the American Pain Society·Michelle T LeonardAyna B Johansen
Nov 8, 2006·Archives of General Psychiatry·Kenji KatoNancy L Pedersen
Oct 17, 2007·Annual Review of Psychology·John D MayerSigal G Barsade
Apr 30, 2008·European Eating Disorders Review : the Journal of the Eating Disorders Association·Laura SouthgateJanet Treasure
Jul 26, 2008·Annals of the Rheumatic Diseases·G J MacfarlaneUNKNOWN European Male Ageing Study Group
Sep 23, 2008·The Clinical Journal of Pain·Annmarie CanoJaclyn B Heller
May 20, 2009·The American Psychologist·Benjamin B Lahey
Oct 27, 2009·The Journal of Pain : Official Journal of the American Pain Society·Mark D BishopMichael E Robinson
Dec 18, 2009·The Journal of Pain : Official Journal of the American Pain Society·Desireé Ruiz-ArandaPablo Fernández-Berrocal
Mar 26, 2010·Depression and Anxiety·Kendra L S OcañezMichael W Otto
Aug 26, 2011·The Journal of Pain : Official Journal of the American Pain Society·Desireé Ruiz-ArandaPablo Fernández-Berrocal
Sep 8, 2012·Annals of the Rheumatic Diseases·Marjolein J PetersJoyce B J van Meurs

❮ Previous
Next ❯

Citations

Dec 10, 2019·Journal of Health Psychology·Octavio Luque-RecaFernando Estévez-López
Jun 14, 2019·Pain Research & Management : the Journal of the Canadian Pain Society = Journal De La Société Canadienne Pour Le Traitement De La Douleur·Aidan C TanDavid Champion
Jan 20, 2020·Neuroscience and Biobehavioral Reviews·Waqas Ullah KhanMarco Battaglia
Mar 9, 2017·The Clinical Journal of Pain·Theresa J DonnellyDavid Champion

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.