PMID: 5919363Sep 1, 1966

A distinctive fraction of alkaline phosphatase in health and disease

Journal of Clinical Pathology
M A Newton

Abstract

An electrophoretic fraction of plasma alkaline phosphatase, which migrates more slowly than the main fraction, was present in one fifth of normal subjects, and in some patients with parenchymal liver disease. It was absent in patients with bone disease, uncomplicated biliary obstruction, and hepatic metastases. The electrophoretic and inhibition properties of this slow band were similar to those of intestinal phosphatase, and its significance is discussed. In a patient with hypophosphatasia this fraction was apparently not decreased.

References

May 15, 1975·Clinica Chimica Acta; International Journal of Clinical Chemistry·A W HODSON, A L LATNER
May 1, 1957·The American Journal of Medicine·D FRASER
Apr 1, 1959·The Journal of Clinical Investigation·I N ROSENBERG
Apr 1, 1960·The American Journal of Medicine·J E BETHUNE, C E DENT
Aug 13, 1962·Biochimica Et Biophysica Acta·W H FishmanN R Inglis
Mar 1, 1962·Clinica Chimica Acta; International Journal of Clinical Chemistry·A W HODSONL RAINE
Jun 1, 1963·Archives of Disease in Childhood·R A GOYER
Jan 1, 1963·Acta Genetica Et Statistica Medica·K E ARFORSL G LUNDIN
Jan 1, 1963·Acta Genetica Et Statistica Medica·K E ARFORSL G LUNDIN
Mar 6, 1965·Lancet·K F BAMFORDT E CLEGHORN
May 1, 1962·Journal of Clinical Pathology·N H KORNER
Jan 1, 1945·The Biochemical Journal·G E Delory

Citations

Dec 1, 1971·The American Journal of Digestive Diseases·M BarakatT Hersh
Oct 1, 1969·Clinica Chimica Acta; International Journal of Clinical Chemistry·L A NagodeC L Steinmeyer
Jun 6, 1968·The New England Journal of Medicine·S H DanovitchL Laster
Oct 1, 1991·Journal of Clinical Pathology·T Kuwana, S B Rosalki
Apr 2, 2005·Annals of Nutrition & Metabolism·Khanh Vinh Quoc Luong, Lan Thi Hoang Nguyen
Oct 1, 1971·The Journal of Clinical Investigation·J B WarshawL L Stolbach
May 1, 1974·The American Journal of Medicine·W H Fishman
Jun 1, 1988·Culture, Medicine and Psychiatry·M K Nations, L A Rebhun
Mar 1, 1982·Critical Reviews in Clinical Laboratory Sciences·P M Crofton
Oct 14, 1969·Annals of the New York Academy of Sciences·W H Fishman

Related Concepts

Alkaline Phosphatase
Bone Diseases
Electrophoresis
Hypophosphatasia
Liver Dysfunction

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