A diversity-oriented strategy for the construction of tetrasubstituted pyrroles via coupled domino processes

Journal of the American Chemical Society
David TejedorMatías López Rodríguez

Abstract

A new microwave-assisted rearrangement of 1,3-oxazolidines scaffolds is the basis for a new, metal-free, direct, and modular construction of tetrasubstituted pyrroles from terminal-conjugated alkynes, aldehydes, and primary amines. This new reaction manifold entails two linked domino processes in a one-pot manner with both atom- and bond-efficiency and under very simple and environment-friendly experimental conditions.

Citations

Jun 21, 2006·Chemical Communications : Chem Comm·David TejedorFernando García-Tellado
Jun 10, 2010·Chemical Communications : Chem Comm·Sandrine Lamandé-LangleJean-Luc Parrain
Apr 7, 2016·Accounts of Chemical Research·David TejedorFernando García-Tellado
Feb 28, 2007·Chemical Society Reviews·David Tejedor, Fernando García-Tellado
Dec 17, 2008·Chemistry : a European Journal·David TejedorFernando García-Tellado
Oct 24, 2007·Chemistry : a European Journal·Benito AlcaideMaría C Redondo
Jan 16, 2009·Angewandte Chemie·David TejedorFernando García-Tellado
Jul 6, 2010·Chemical Society Reviews·Verónica EstévezJ Carlos Menéndez
Feb 18, 2011·Chemistry : a European Journal·David TejedorFernando García-Tellado
May 13, 2009·Organic Letters·Eugen MerkulThomas J J Müller
Nov 24, 2004·Angewandte Chemie·C Oliver Kappe
Oct 29, 2010·The Journal of Organic Chemistry·Yuanzhi Xia, Genping Huang
Feb 22, 2013·The Journal of Organic Chemistry·David TejedorFernando García-Tellado
Apr 17, 2019·The Journal of Organic Chemistry·Wenbo HuangYanlong Gu
Mar 9, 2011·The Journal of Organic Chemistry·Tobias Harschneck, Stefan F Kirsch
Aug 24, 2007·The Journal of Organic Chemistry·Ines Bergner, Till Opatz
Jul 11, 2006·Journal of Combinatorial Chemistry·Ivana BianchiLuca F Raveglia
Aug 4, 2005·Journal of the American Chemical Society·Yoshihiko YamamotoHisao Nishiyama
Jan 29, 2005·The Journal of Organic Chemistry·David TejedorFernando García-Tellado

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