A DNA logic gate based on strand displacement reaction and rolling circle amplification, responding to multiple low-abundance DNA fragment input signals, and its application in detecting miRNAs

Chemical Communications : Chem Comm
Yuqi ChenXiang Zhou

Abstract

A conveniently amplified DNA AND logic gate platform was designed for the highly sensitive detection of low-abundance DNA fragment inputs based on strand displacement reaction and rolling circle amplification strategy. Compared with others, this system can detect miRNAs in biological samples. The success of this strategy demonstrates the potential of DNA logic gates in disease diagnosis.

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Citations

Nov 5, 2015·Angewandte Chemie·Dick Yan TamPik Kwan Lo
May 19, 2017·Applied Biochemistry and Biotechnology·Tahereh FozooniHosseinali Sasan
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Oct 3, 2017·Chemical Communications : Chem Comm·Kunli ZhaoShouzhuo Yao
Jan 23, 2021·ACS Synthetic Biology·Alan F Rodríguez-Serrano, I-Ming Hsing
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Sep 26, 2017·Journal of the American Chemical Society·Kunihiko MorihiroAlexander Deiters

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