A dosimetric analysis of cardiac dose with or without active breath coordinator moderate deep inspiratory breath hold in left sided breast cancer radiotherapy

Journal of Cancer Research and Therapeutics
Beena KunheriDinesh Makuny

Abstract

Cardiac toxicity is a major concern for left breast tangential field irradiation. The left ventricle and left anterior descending (LAD) artery are suggested to be radiosensitive and radiation to these structures leads to late lethal cardiotoxicity. Moderate deep inspiration breath hold (mDIBH) during radiation treatment delivery helps in reducing the cardiac dose. This study compares dosimetric parameters of heart with and without active breath coordinator (ABC) mDIBH during tangential field breast cancer radiation. This is a dosimetric comparative study. Forty-five consecutive patients with left-sided breast cancer who underwent breast-conserving surgery and adjuvant tangential field and radiotherapy with ABC mDIBH between November 2013 and September 2015 in our center were analyzed in this study. The ABC device was used for respiratory control and patients who could hold their breath for 20-30 s were considered for radiation with ABC mDIBH. Simulation scans of both free breathing (FB) and ABC mDIBH were done. Tangent field treatment plans with a dose prescription of 40 Gy/15 Fr were generated for each patient, in both scans. Target coverage, dose to the heart, LAD, and the left lung were documented with dose-volume histograms...Continue Reading

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Citations

Nov 11, 2019·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Junming LaiXin Long
Dec 10, 2019·World Journal of Clinical Oncology·Omer SagerMurat Beyzadeoglu
Oct 7, 2020·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Jensen ReckhowShira Galper
Apr 29, 2021·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Kimiko HirataShuji Ohtsu

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