Abstract
To evaluate the role of intensity-modulated radiation treatment (IMRT) as an alternative to high-dose-rate (HDR) brachytherapy in the treatment of the vagina in postoperative early endometrial cancer patients after surgery. Planning computed tomography (CT) scans of 10 patients previously treated with HDR were used in this study. In all cases, a dose of 700 cGy/fraction was prescribed at a distance of 0.5 cm from the cylinder surface. The same CT scans were then used in IMRT planning. In this paradigm, the vaginal cylinder represents a component of a hypothetical immobilization system that would be indexed to the linac treatment table. Our study showed that IMRT provided relatively lower rectal doses than HDR when treatment was prescribed at a distance of 0.5 cm away from the cylinder surface. Maximum rectal doses were lower with IMRT compared with HDR (average: 89.0% vs. 142.6%, respectively, p < 0.05). Moreover, the mean rectal dose was lower in IMRT plans compared with HDR plans with treatment prescribed either to the surface (average: 14.8% vs. 21.4%, respectively, p < 0.05) or to 0.5 cm (average: 19.6% vs. 33.5%, respectively, p < 0.05). IMRT plans had planning target volume (PTV) coverage comparable with HDR (average PTV ...Continue Reading
References
Jul 4, 1998·International Journal of Radiation Oncology, Biology, Physics·M Zaider, H I Amols
Jan 21, 2000·Cancer·D J BrennerE Ron
Aug 5, 2000·International Journal of Radiation Oncology, Biology, Physics·S NagD Petereit
Oct 6, 2000·International Journal of Radiation Oncology, Biology, Physics·S NagG Glasgow
Dec 21, 2000·International Journal of Radiation Oncology, Biology, Physics·J C RoeskeA J Mundt
Aug 23, 2001·International Journal of Radiation Oncology, Biology, Physics·L PortelanceD Low
Apr 17, 2002·International Journal of Radiation Oncology, Biology, Physics·Arno J MundtJohn C Roeske
Apr 16, 2003·International Journal of Radiation Oncology, Biology, Physics·Eric J Hall, Cheng-Shie Wuu
Feb 21, 2004·CA: a Cancer Journal for Clinicians·Ahmedin JemalUNKNOWN American Cancer Society
May 6, 2004·Medical Physics·Sasha H WahabDaniel A Low
Aug 12, 2004·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·A Ahamad, A Jhingran
Jun 7, 2005·International Journal of Radiation Oncology, Biology, Physics·Mariana GuerreroBeth Erickson
Citations
Jun 18, 2011·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Silvia Rodríguez VillalbaJosé Manuel Cervera Grau
Sep 3, 2013·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·J-M Hannoun-Lévi, D Peiffert
Jan 5, 2013·Radiation Oncology·Fernanda G HerreraMahmut Ozsahin
Jul 7, 2011·Journal of Medical Physics·B ShwethaS Sathiyan
Jun 26, 2012·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Savino CillaAlessio G Morganti
Mar 3, 2012·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Piernicola PediciniVincenzo Fusco
Dec 24, 2011·Brachytherapy·Mustafa CengizFaruk Zorlu
Jun 12, 2010·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Benjamin T GieldaKatherine L Griem
Oct 6, 2009·International Journal of Radiation Oncology, Biology, Physics·Gabriella MacchiaAlessio Giuseppe Morganti
Aug 22, 2009·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·I Barillot
Jul 22, 2008·International Journal of Radiation Oncology, Biology, Physics·Loren K MellBulent Aydogan
May 23, 2008·International Journal of Radiation Oncology, Biology, Physics·Dietmar GeorgRichard Pötter
Jan 1, 2008·International Journal of Radiation Oncology, Biology, Physics·Jun DuanSui Shen
May 29, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Isabelle Barillot
Oct 3, 2006·International Journal of Radiation Oncology, Biology, Physics·Alison Cameron, Paul Cornes
Jul 25, 2008·Medical Physics·Youngyih HanYong Chan Ahn
Mar 9, 2013·Journal of Applied Clinical Medical Physics·Piernicola PediciniMarco Salvatore
Jan 5, 2010·Yonsei Medical Journal·Hee Chul ParkHiroki Shirato
Jul 30, 2008·Acta Oncologica·Marianne S AssenholtKari Tanderup
Mar 20, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Roberta LazzariBarbara Alicja Jereczek-Fossa
Jun 23, 2020·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Savino CillaAlessio G Morganti