A dosimetric comparison of whole-lung treatment techniques in the pediatric population

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
Christina L BosargeJeffrey C Buchsbaum

Abstract

To demonstrate the dosimetric advantages and disadvantages of standard anteroposterior-posteroanterior (S-AP/PAAAA), inverse-planned AP/PA (IP-AP/PA) and volumetry-modulated arc (VMAT) radiotherapies in the treatment of children undergoing whole-lung irradiation. Each technique was evaluated by means of target coverage and normal tissue sparing, including data regarding low doses. A historical approach with and without tissue heterogeneity corrections is also demonstrated. Computed tomography (CT) scans of 10 children scanned from the neck to the reproductive organs were used. For each scan, 6 plans were created: (1) S-AP/PAAAA using the anisotropic analytical algorithm (AAA), (2) IP-AP/PA, (3) VMAT, (4) S-AP/PANONE without heterogeneity corrections, (5) S-AP/PAPB using the Pencil-Beam algorithm and enforcing monitor units from technique 4, and (6) S-AP/PAAAA[FM] using AAA and forcing fixed monitor units. The first 3 plans compare modern methods and were evaluated based on target coverage and normal tissue sparing. Body maximum and lower body doses (50% and 30%) were also analyzed. Plans 4 to 6 provide a historic view on the progression of heterogeneity algorithms and elucidate what was actually delivered in the past. Averages ...Continue Reading

References

Apr 16, 2003·International Journal of Radiation Oncology, Biology, Physics·Eric J Hall, Cheng-Shie Wuu
Apr 19, 2006·International Journal of Radiation Oncology, Biology, Physics·Eric J Hall
Dec 5, 2009·Seminars in Radiation Oncology·Andrea K NgLois B Travis
Jul 24, 2012·International Journal of Radiation Oncology, Biology, Physics·John A KalapurakalMahesh Gopalakrishnan

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